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<p><span style="color:black">Deadline extended to March 5<sup>th </sup>– still time to apply<o:p></o:p></span></p>
<p><span style="color:black">----------------------------------------------------<o:p></o:p></span></p>
<p><span style="color:black">dear all,</span><span style="font-size:11.0pt"><o:p></o:p></span></p>
<p><span style="color:black">Two 3-year postdoctoral position are available at <b>
Imperial College London</b> to work on the mechanisms of <b>eukaryotic replication</b> or
<b>chromatin structure</b> using biochemistry and cryo-EM. Deadline is </span>5<sup>th</sup> of March<span style="color:black"> 2020.</span><o:p></o:p></p>
<p><span style="color:black">The <b>Speck Lab</b> works on initiation of eukaryotic DNA replication & the structure of chromatin + its regulation by epigenetic changes. We are looking for a passionate researcher with</span> extensive expertise in Biochemistry
and/or Structural Biology.<o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span style="color:black"> </span><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><b><span style="color:black">Research framework and support structure: </span></b><o:p></o:p></p>
<ol start="1" type="1">
<li class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo2;background:white">
The group consists of >10 members, 6 postdocs, 3 students, lab manager and technician.
<o:p></o:p></li><li class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo2;background:white">
The lab is fully equipped for biochemistry (2 AKTAs, multiple temperature controlled shakers), two freezer mills, Biacore T100 and generously supported by the Wellcome Trust and multiple BBSRC grants.<o:p></o:p></li><li class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo2;background:white">
Access to state-of-the-art facilities including Mass Spectrometry, Structural Biology and Bioinformatics.<o:p></o:p></li><li class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo2;background:white">
The candidate will receive direct mentoring by the group head on grant applications, writing of manuscripts and project design.<o:p></o:p></li><li class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;mso-list:l0 level1 lfo2;background:white">
We have direct access to a local cryo-EM facility with a 200KV FEG microscope and the LonCEM facility with a Krios (K3 & Falcon 3 detectors, phase plate, energy filter,..).
<o:p></o:p></li></ol>
<p class="MsoNormal" style="background:white"><span style="color:black"> Interested individuals are welcome to contact me directly for more information.</span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;mso-fareast-language:EN-US"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="color:black"> </span><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span style="color:black">Best,</span><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span style="color:black">Christian</span><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><a href="mailto:chris.speck@imperial.ac.uk"><span style="color:#2402EE">chris.speck@imperial.ac.uk</span></a><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span style="color:black"> </span><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><b><span style="color:black">here are a few links:</span></b><o:p></o:p></p>
<p class="MsoNormal" style="background:white"> <o:p></o:p></p>
<p class="MsoNormal" style="background:white">you can apply here:<o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span style="color:black"> </span><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><a href="https://www.imperial.ac.uk/jobs/description/MED01698/research-associate"><span style="color:blue">https://www.imperial.ac.uk/jobs/description/MED01698/research-associate</span></a><span style="color:blue"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="color:#1F497D"> </span><span style="font-size:11.0pt"><o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="color:black">The group:</span><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span style="color:black"> </span><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><a href="http://www.specklab.com/"><span style="color:#2402EE">http://www.specklab.com/</span></a><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span style="color:black"> </span><o:p></o:p></p>
<p class="MsoNormal" style="background:white"><span style="color:black"> </span><o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">__________________________________________</span></i><i><span style="font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p></o:p></span></i></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Professor Christian Speck, PhD, FRSB<o:p></o:p></span></i></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Chair in Genome Biochemistry & Molecular Biology</span></i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Wellcome Trust Investigator<o:p></o:p></span></i></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p> </o:p></span></i></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Imperial College London<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Faculty of Medicine<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Institute of Clinical Sciences (CRB room 3006)<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Hammersmith Hospital Campus<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Du Cane Road<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">London W12 0NN<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Tel: 0044 20 8383 3387
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Mobile: 0044 796 181 5557<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">Skype ID: dna_rep<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">email:
</span></i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D"><a href="mailto:christian.speck@imperial.ac.uk"><span style="color:blue;mso-fareast-language:DE">christian.speck@imperial.ac.uk</span></a></span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#1F497D;mso-fareast-language:DE">website:
</span></i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D"><a href="http://www.specklab.com/"><i><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:blue;mso-fareast-language:DE">www.specklab.com</span></i></a></span><i><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#1F497D;mso-fareast-language:DE">
</span></i><i><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:red;mso-fareast-language:DE"><o:p></o:p></span></i></p>
<p class="MsoNormal"><i><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:#1F497D;mso-fareast-language:DE">Imperial College website:</span></i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE">
</span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D"><a href="http://www.imperial.ac.uk/people/chris.speck"><i><span style="color:blue;mso-fareast-language:DE">www.imperial.ac.uk/people/chris.speck</span></i></a></span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D"><img border="0" width="354" height="111" style="width:3.6916in;height:1.1583in" id="Picture_x0020_1" src="cid:image001.jpg@01D5EC87.DA094B80" alt="http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtvm050463.jpg">
<img border="0" width="227" height="139" style="width:2.3666in;height:1.45in" id="Picture_x0020_2" src="cid:image002.png@01D5EC87.DA094B80" alt="cid:image002.png@01D33B79.8BEFDA70"></span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D;mso-fareast-language:DE"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;mso-fareast-language:EN-US"><o:p> </o:p></span></p>
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