<div dir="ltr"><p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">Dear colleagues, </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">We are currently looking for a postdoctoral researcher
to join our lab. Please see below for details:</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">OFFER</span></b><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> – Postdoctoral Position (Two years)</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">DEADLINE: </span></b><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">4<sup>th</sup> of February, 2020 at 17:00 h CET or until position is
filled.<b></b></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">WHERE</span></b><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> – Basque
Centre for Biophysics (Bilbao, SPAIN)</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">The Basque Centre for Biophysics is an international research
center of excellence with the main aim of promoting a multidisciplinary research
program in the field of Biophysics and its application in the areas of Biotechnology
and Health, the center is a joint effort of the University of the Basque
Country (UPV/EHU) and the Spanish National Research Council (CSIC).<b></b></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">Description of the position offered</span></b></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">The position is available in the Structural
Microbiology Laboratory led by Dr. David Albesa-Jové at the Basque Centre for
Biophysics (Bilbao, Spain). Our group was recently established and focuses on
understanding the biological function of virulence factors and essential
enzymes in human pathogenic bacteria. Please, see below for some recent
publications. The laboratory is well equipped for all aspects of molecular
biology, biochemistry, biophysics and crystallography. We also have regular
access to synchrotron radiation at Diamond (UK) and ALBA (Spain) through BAG
applications.</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif;color:rgb(51,51,51);background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.25pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif">1.    <b>Albesa-Jové*</b> D, et al.: Structural
Snapshots of </span><span style="font-family:Arial,sans-serif">α</span><span lang="EN-US" style="font-family:Arial,sans-serif">-1,3-Galactosyltransferase
with Native Substrates: Insight into the Catalytic Mechanism of Retaining
Glycosyltransferases. </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.25pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><u><span lang="EN-US" style="font-family:Arial,sans-serif">Angew Chemie Int Ed</span></u><span lang="EN-US" style="font-family:Arial,sans-serif"> 2017,
56:14853–14857. <i><span style="color:rgb(0,43,255)">IF.
12.26 </span><span style="color:rgb(0,32,96)">*corresponding author</span></i></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.25pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif">2.    Planamente S, Salih O, Manoli E, <b>Albesa</b></span><b><span lang="EN-US" style="font-family:"Cambria Math",serif">‐</span></b><b><span lang="EN-US" style="font-family:Arial,sans-serif">Jové D</span></b><span lang="EN-US" style="font-family:Arial,sans-serif">, Freemont PS, Filloux A: TssA
forms a gp6</span><span lang="EN-US" style="font-family:"Cambria Math",serif">‐</span><span lang="EN-US" style="font-family:Arial,sans-serif">like ring
attached to the type VI secretion sheath</span><span lang="EN-US" style="font-family:Arial,sans-serif">. <i></i></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.25pt;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><i><u><span lang="EN-US" style="font-family:Arial,sans-serif">EMBO J.</span></u></i><span lang="EN-US" style="font-family:Arial,sans-serif"> 2016, 35:1613–1627.
</span><i><span lang="EN-US" style="font-family:Arial,sans-serif;color:rgb(0,43,255)">IF. 11.23</span></i><span lang="EN-US" style="font-family:Arial,sans-serif"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.3pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif">3.    <b>Albesa-Jové </b>D, et al.</span><span lang="EN-US" style="font-family:Arial,sans-serif">: Structural basis for selective recognition of
acyl chains by the membrane-associated acyltransferase PatA</span><span lang="EN-GB" style="font-family:Arial,sans-serif"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif">              </span><u><span lang="EN-US" style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">Nature Communications</span></u><span lang="EN-US" style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial">. 2016, 7:10906. </span><i><span lang="EN-US" style="font-family:Arial,sans-serif;color:rgb(0,43,255)">IF. 11.89</span></i><span lang="EN-US" style="font-family:Arial,sans-serif;background-image:initial;background-position:initial;background-size:initial;background-repeat:initial;background-origin:initial;background-clip:initial"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.3pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif">4.    <b>Albesa-Jové</b> D, et al.</span><span lang="EN-US" style="font-family:Arial,sans-serif">: A
native ternary complex in crystal reveals the catalytic mechanism of a retaining
glycosyltransferase.</span><span lang="EN-GB" style="font-family:Arial,sans-serif"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.3pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif">       <u>Angew Chem Int Ed Engl.</u>
2015; 54(34): 9898-902. <i><span style="color:rgb(0,43,255)">IF. 12.26</span></i></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.3pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif">5.    Giganti D, <b>Albesa-Jové</b> D, et al.: Secondary structure reshuffling modulates
glycosyltransferase function at the membrane.</span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.3pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif">       <u>Nature Chemical Biology.</u> 2015,
11(1): 16–18. <i><span style="color:rgb(0,43,255)">IF.
12.15</span></i></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.3pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-family:Arial,sans-serif">6.    Andrés A<sup>1</sup>, <b>Albesa-Jové<sup>1</sup></b>
D, et al.</span><span lang="EN-US" style="font-family:Arial,sans-serif">: Structural
basis of chitin oligosaccharide deacetylation. </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 3pt 21.3pt;text-align:justify;line-height:107%;font-size:11pt;font-family:Calibri,sans-serif"><u><span lang="EN-US" style="font-family:Arial,sans-serif">Angew
Chem Int Ed Engl.</span></u><span lang="EN-US" style="font-family:Arial,sans-serif"> 2014, 53(27): 6882</span><span lang="EN-US" style="font-family:Arial,sans-serif">–6887. <i><span style="color:rgb(0,43,255)">IF. 12.26 </span><sup><span style="color:rgb(0,32,96)">1</span></sup><span style="color:rgb(0,32,96)">equal contribution</span></i></span><span lang="EN-GB" style="font-family:Arial,sans-serif"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">Education and Experience Required</span></b></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">We are seeking a highly motivated individual with a
strong background in structural biology, including protein expression and
purification, protein crystallization, and X-ray crystallography. Outstanding
postdoctoral candidates will also have the necessary support to apply for the
Ikerbasque Fellows 2020 call. These 5-year Fellowships are directed to
promising young postdoctoral researchers (applicants must have their PhD
completed between 2009 and 2017) and are intended to offer a track towards
independent research as a group leader. Ikerbasque Fellows in their 5<sup>th</sup>
year can be assessed for permanent group leader positions. More details about
the previous 2019 Ikerbasque Fellows call can be found here: </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><a href="http://www.ikerbasque.net/sites/default/files/files/Ikerbasque_RF_2019_Call_Specifications.pdf" style="color:rgb(5,99,193)"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">http://www.ikerbasque.net/sites/default/files/files/Ikerbasque_RF_2019_Call_Specifications.pdf</span></a><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"></span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> </span></p>

<p class="MsoNormal" style="margin:0cm 0cm 0.0001pt;text-align:justify;line-height:normal;font-size:11pt;font-family:Calibri,sans-serif"><b><u><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif">Contact:</span></u></b><span lang="EN-US" style="font-size:12pt;font-family:"Times New Roman",serif"> Please submit your application for the postdoctoral
position through the Centre’s website (<a href="http://biofisika.org/contact/">http://biofisika.org/contact/</a>)
indicating the following subject: <b>Job
Application: 52Albesa</b>, and adding a cover letter, curriculum vitae, and
contact information for three professional referees. Informal enquires can be
directed to <a href="mailto:davidalbesa@gmail.com" style="color:rgb(5,99,193)">davidalbesa@gmail.com</a>.
Women are encouraged to apply.</span></p></div>