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<span style="font-size:13.5pt;font-family:"Helvetica Neue";color:white">A 3 year PhD fellowship is available in the Group of Structural Biology and Drug Development (<a href="https://www.med.uio.no/ncmm/english/groups/luecke-group/"><span style="color:white">Luecke
group</span></a>) at the Centre for Molecular Medicine Norway (NCMM), University of Oslo (UiO).<o:p></o:p></span></p>
<p style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:15.0pt;margin-left:0in;background:#44303C;box-sizing: border-box;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<span style="font-size:13.5pt;font-family:"Helvetica Neue";color:white">The Group for Structural Biology and Drug Development investigates medically relevant proteins and protein complexes using biophysical, biochemical and structural approaches. The projects
aim at understanding structure-function relationships with an emphasis on drug discovery. We employ a variety of biochemical and biophysical techniques (x-ray crystallography, single particle cryo electron microscopy, DSF, ITC, SPR, HDX-MS, SAXS, molecular
dynamics simulations etc.). Externally funded projects include inhibitor discovery targeting the Helicobacter pylori pH acclimation system (a pH-gated urea channel and a cytoplasmic urease), and discovery of compounds that reactivate p53 cancer mutants in
vitro and in vivo. Additional projects are available.<o:p></o:p></span></p>
<p style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:15.0pt;margin-left:0in;background:#44303C;box-sizing: border-box;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<span style="font-size:13.5pt;font-family:"Helvetica Neue";color:white">The PhD student will also benefit from career development programs offered both at UiO, the <a href="http://site.uit.no/biocat/"><span style="color:white">Norwegian BioCat initiative </span></a>as
well as the Nordic EMBL network of the Centre for Molecular Medicine, Norway.<o:p></o:p></span></p>
<p class="MsoNormal" style="text-autospace:none"><span style="font-size:11.0pt;color:black">Online application required, deadline 31 Mar 2019:<o:p></o:p></span></p>
<p class="MsoNormal" style="text-autospace:none"><span style="font-size:11.0pt;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-autospace:none"><span style="font-size:11.0pt;color:black">https://www.jobbnorge.no/en/available-jobs/job/164159/two-2-postdoctoral-fellowships-in-structural-biology-and-drug-development
<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span lang="NO-BOK" style="color:black"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black">--<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black">Prof. Hartmut Luecke<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black">Structural Biology and Drug Discovery Group<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black">Norwegian Centre for Molecular Medicine (NCMM), Nordic EMBL Partnership <o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black">and Institute of Clinical Medicine, University of Oslo<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black">Dept. of Medical Biochemistry, Oslo University Hospital<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Arial",sans-serif;color:black">Oslo, Norway</span></p>
<p class="MsoNormal" style="text-align:justify;text-autospace:none"><span lang="NO-BOK" style="color:black"><o:p> </o:p></span></p>
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