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<span style="font-size:9.5pt;line-height:115%;font-family:Arial,sans-serif">Dear colleagues, </span><span style="color:black"></span></p>
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<span style="font-size:9.5pt;line-height:115%;font-family:Arial,sans-serif">A cryo-EM specialist position at the Harvard Cryo-EM Center for Structural Biology is currently available. See below for a detailed job description and how to apply. Please share
this message with all who are interested. Your help is greatly appreciated.</span><span style="color:black"></span></p>
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<b><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black">Cryo-EM Specialist position at the Harvard Cryo-EM Center for Structural Biology</span></b><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black"></span></p>
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<b><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black"> </span></b><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black"></span></p>
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<span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black">Harvard Medical School, Boston Children's Hospital, Dana-Farber Cancer Institute, and Massachusetts General
</span><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black">Hospital have joined to create a new cryo-EM center for structural biology in the Harvard community (</span><span class="gmail-MsoHyperlink" style="color:blue;text-decoration-line:underline"><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:rgb(17,85,204)"><a href="https://cryoem.hms.harvard.edu/" target="_blank" style="color:blue"><span style="color:rgb(17,85,204)">https://cryoem.hms.harvard.edu/</span></a></span></span><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif">)</span><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black">.
The facility opened at the end of 2018 and currently houses two FEI Titan Krios electron microscopes each equipped with Volta phase plates, BioQuantum GIF and a K3 direct detector and one FEI Talos Arctica electron microscope equipped with Volta phase plates
and K2 direct detector (upgrade to K3 planned in 2019). We seek personnel who will train users, operate the microscopes and interface with a vibrant scientific user community. This position is ideal for scientists keen to use their skills to contribute to
multiple projects from many research areas and to take on science management responsibilities.</span></p>
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<span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black"> </span></p>
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<b><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black">Job description.</span></b><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black"> (1) Serve as the technical interface between the user
and the microscopes: check microscope alignment, insert grids, set up users to record images. (2) Train users in cryo-grid preparation, in operation of software that runs the microscope and records the images. (3) Advise users on experimental strategy or
(when appropriate) collaborate with them to assist in data recording, analysis, and structure determination. (4) Assist the faculty director in managing the facility, working closely with a team of cryo-EM specialists and the facility director to maintain
and operate the microscopes and keep records of daily operations.</span></p>
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<span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black"> </span></p>
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<span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black">This position will have a high degree of independence, opportunities to present at regional and national scientific symposia and workshops, and opportunities to develop collaborative
relationships with Harvard investigators.</span></p>
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<span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black"> </span></p>
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<b><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black">Requirements.</span></b><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black"> (1) Ph.D. in a field related to structural biology such
as cell biology or biochemistry. Experience in structural biology -- either x-ray crystallography or electron microscopy (or both) -- ideally at the postdoctoral level. Moderate or extensive EM experience preferred. Experience with cryo electron tomography
is a plus. (2) Good communication and interpersonal skills with attention to detail and a commitment to excellence. (3) Expertise in operating complex instrumentation and experience with sophisticated software systems. (4) Interest in becoming cryoEM expert
</span><span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black">and learning how to align and operate high-end microscopes at a very sophisticated level. (Potential career track as EM facility director, for example.)</span></p>
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<span style="font-size:11pt;line-height:115%;font-family:Arial,sans-serif;color:black"> </span></p>
<span style="font-size:11pt;font-family:Arial,sans-serif;color:black">To apply, please submit a cover letter and CV to the director, Dr. Stephen Harrison, via </span><u><span style="font-size:11pt;font-family:Arial,sans-serif;color:blue"><a href="mailto:schadmin@crystal.harvard.edu" target="_blank" style="color:blue">schadmin@crystal.harvard.edu</a></span></u><span style="font-size:11pt;font-family:Arial,sans-serif;color:black">.
In the Subject line of your email, please write: Cryo-EM Specialist. </span> <br clear="all">
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<div dir="ltr"><font face="trebuchet ms, sans-serif"><span style="color:rgb(102,102,102)">-----</span></font></div>
<div dir="ltr"><font face="trebuchet ms, sans-serif"><span style="color:rgb(102,102,102)">Sarah Sterling, Ph.D.</span><br>
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<span style="color:rgb(102,102,102)">The Harvard Cryo-EM Center </span><span style="color:rgb(102,102,102)">for Structural Biology </span></font></div>
<div dir="ltr"><font face="trebuchet ms, sans-serif"><span style="color:rgb(102,102,102)">Harvard Medical School</span></font></div>
<div dir="ltr"><font face="trebuchet ms, sans-serif"><span style="color:rgb(102,102,102)">250 Longwood Avenue</span></font></div>
<div dir="ltr"><font face="trebuchet ms, sans-serif"><span style="color:rgb(102,102,102)">SGM 104, BCMP</span></font></div>
<div dir="ltr"><font face="trebuchet ms, sans-serif"><span style="color:rgb(102,102,102)">Boston, MA 02115</span><br>
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<div><font color="#666666" face="trebuchet ms, sans-serif">Phone: (617) 432-7091<br>
Email: <a href="mailto:Sarah_Sterling@hms.harvard.edu" style="color:rgb(17,85,204)" target="_blank">Sarah_Sterling@hms.harvard.edu</a></font></div>
<div><font color="#666666" face="trebuchet ms, sans-serif">Web: <a href="http://cryoem.hms.harvard.edu/" style="color:rgb(17,85,204)" target="_blank">cryoem.hms.harvard.edu</a></font></div>
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