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<div class="">Dear All,</div>
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<div class="">Please see below for details of a Postdoctoral Fellow position in my team (available immediately).</div>
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<div class="">Thank you and best wishes,</div>
<div class="">Sebastian</div>
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<div class="">A <b class="">Postdoctoral Fellow position in Biochemistry/Biophysics and Cryo-Electron Microscopy</b> is available in the laboratory of <b class="">Dr Sebastian Guettler </b>at the<b class=""> Institute of Cancer Research (ICR) in London, UK</b>.</div>
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<div class="">The Postdoctoral Fellow will analyse the function of <b class="">poly(ADP-ribose)polymerase (PARP) enzymes</b> by using a combination of biochemical, biophysical and structural biology approaches. The emphasis will be on the structural characterisation
of proteins/protein complexes by <b class="">single-particle cryo-EM</b> and associated biochemical/biophysical studies.</div>
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<div class="">Work in the Guettler laboratory centres on the elucidation of signal transduction mechanisms relevant to the function of cancer cells, in particular the Wnt/beta-catenin network and telomere homeostasis and their control by poly(ADP-ribosyl)ation.
For details, please visit <a href="http://sguettlerlab.org" class="">sguettlerlab.org</a> and <a href="http://icr.ac.uk" class="">icr.ac.uk</a>.</div>
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<div class="">The Division of Structural Biology has managed facilities for protein production (with expertise in multi-subunit protein complex expression), protein crystallography, cryo-EM and biophysics. Regular access to Titan Krios instruments at the Electron
Bio-Imaging Centre (eBIC) at Diamond Light Source is available through a Block Allocation Group. Moreover, The Institute of Cancer Research is part of the London Consortium for Cryo-Electron Microscopy, hosting a Titan Krios instrument based at the Francis
Crick Institute (available in early 2019). The Division of Structural Biology is located at ICR’s Chelsea site in central London.</div>
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<div class=""><b class="">For further details and to apply, please visit the ICR Careers portal:</b></div>
<div class=""><a href="https://icr.tal.net/vx/appcentre-ext/brand-0/candidate/so/pm/1/pl/1/opp/546-Post-doctoral-Training-Fellow-Biochemistry-Biophysics-and-Cryo-Electron-Microscopy/en-GB" class="">https://icr.tal.net/vx/appcentre-ext/brand-0/candidate/so/pm/1/pl/1/opp/546-Post-doctoral-Training-Fellow-Biochemistry-Biophysics-and-Cryo-Electron-Microscopy/en-GB</a></div>
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<div class="">Informal enquiries can be made to <a href="mailto:sebastian.guettler@icr.ac.uk" class="">sebastian.guettler@icr.ac.uk</a>. (Please note that formal applications must be submitted online.)</div>
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<div class=""><b class="">Closing date: 11 November 2018</b></div>
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<div class="">-----------------------------------------------------------<br class="">
Sebastian Guettler, PhD<br class="">
Team Leader<br class="">
The Institute of Cancer Research (ICR)<br class="">
Divisions of Structural and Cancer Biology<br class="">
237 Fulham Road<br class="">
London, SW3 6JB<br class="">
United Kingdom<br class="">
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e-mail: <a href="mailto:sebastian.guettler@icr.ac.uk" class="">sebastian.guettler@icr.ac.uk</a></div>
<div class="">web:<font color="#954f72" class=""> <a href="http://icr.ac.uk" class="">icr.ac.uk</a> </font> <a href="http://sguettlerlab.org" class="">sguettlerlab.org</a><br class="">
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The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company Limited by Guarantee, Registered in England under Company No. 534147 with its Registered Office at 123 Old Brompton Road, London SW7 3RP.<BR>
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