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<p class="MsoNormal"><span style="font-family:"Calibri","sans-serif";color:#1F497D">Thank you very much Prof Serysheva!<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri","sans-serif";color:#1F497D">Regards<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri","sans-serif";color:#1F497D">Medha<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Calibri","sans-serif";color:#1F497D"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:black;text-transform:uppercase">MEDHA J. TOMLINSON, PH.D.</span></b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:black">Principal Research Scientist</span><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#071D49">Abbvie Bioresearch Center</span></b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:black">Global Biologics – Protein Sciences</span><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:black">100 Research Drive</span><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:black">Worcester, MA 01605</span><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D"><o:p></o:p></span></p>
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</span></b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D"> <a href="mailto:Medha.Tomlinson@abbvie.com"><span style="color:black">Medha.Tomlinson@abbvie.com</span></a><o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:11.25pt"><b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#071D49"><a href="http://www.abbvie.com/"><span style="color:#071D49">abbvie.com</span></a><o:p></o:p></span></b></p>
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<p class="MsoNormal" style="text-align:justify"><span style="font-size:8.0pt;font-family:"Calibri","sans-serif";color:#414141">This communication may contain information that is proprietary, confidential, or exempt from disclosure. If you are not the intended
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<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif"">From:</span></b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif""> Serysheva, Irina I [mailto:Irina.I.Serysheva@uth.tmc.edu]
<br>
<b>Sent:</b> Wednesday, August 08, 2018 10:54 AM<br>
<b>To:</b> 3dem@ncmir.ucsd.edu<br>
<b>Cc:</b> Tomlinson, Medha J<br>
<b>Subject:</b> [EXTERNAL] JOB POSTING: Senior Scientist II, Protein Purification, Discovery, Global Biologics<o:p></o:p></span></p>
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<p class="MsoNormal"><o:p> </o:p></p>
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<p class="MsoNormal"><span style="font-size:18.0pt;font-family:"Calibri","sans-serif"">Dear All, </span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:18.0pt;font-family:"Calibri","sans-serif"">Here is a job posting o</span><span style="font-size:11.0pt;font-family:"Arial","sans-serif"">n behalf of <b><span style="color:#071D49">Abbvie Bioresearch Center, </span></b>Global
Biologics – Protein Sciences </span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<h4 style="margin:0in;margin-bottom:.0001pt;line-height:20.25pt;background:white;vertical-align:baseline;font-variant-ligatures: normal;font-variant-numeric: inherit;font-variant-east-asian: inherit;font-weight:inherit;font-stretch: inherit;orphans: 2;widows: 2;border-top-left-radius: 0px !important;border-top-right-radius: 0px !important;border-bottom-right-radius: 0px !important;border-bottom-left-radius: 0px !important">
<span style="font-size:13.0pt;font-family:"Helvetica","sans-serif";color:#2D2926"><a href="https://abbvie.referrals.selectminds.com/jobs/4049/other-jobs-matching/location-only"><span style="font-family:"inherit","serif";color:#0082BA;border:none windowtext 1.0pt;padding:0in;text-decoration:none">USA,
Massachusetts, Worcester</span></a><o:p></o:p></span></h4>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Calibri","sans-serif""><a href="https://urldefense.proofpoint.com/v2/url?u=https-3A__abbvie.referrals.selectminds.com_jobs_senior-2Dscientist-2Dii-2Dprotein-2Dpurification-2D4049&d=DwMFAg&c=6vgNTiRn9_pqCD9hKx9JgXN1VapJQ8JVoF8oWH1AgfQ&r=favpEJAb1iNy50hxGWh68yD7hRr1EiS8eV6t1DT_lgE&m=7Nz6zBFkJqGcb3SWPwbr67fM9EJSHnS6XuoFpS4j1Oo&s=XPF1sPWiQ9pdxclL7UFF6l-9Z8h6zCyt8ykV-v5Lkws&e="><span style="color:purple">https://abbvie.referrals.selectminds.com/jobs/senior-scientist-ii-protein-purification-4049</span></a></span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-family:"Calibri","sans-serif""> </span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<p class="m-8365309022912125717msoplaintext"><b>Job Description </b><o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">The Global Protein Sciences (GPS) Group is seeking a highly motivated Senior Scientist to join its Protein Purification Group at AbbVie Bioresearch Center in Worcester, MA. As a member of the group, the candidate
will be responsible for working in cross functional teams with other scientists in various therapeutic areas as well as the Biologics generation group in Worcester to advance the pipeline. The successful candidate will have experience in protein engineering
and purification of immunogens and therapeutics with a good understanding of technologies for generating proprietary biotherapeutics.<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext"><b>Key Responsibilities Include:</b><o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Design alternate therapeutic formats (Multi-specifics, Non-Ig Scaffolds etc.), fusion proteins, immunogens from concept using computational tools (Rosetta/pymol/others) and execute through experimental production
and characterization<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Enable progression of targets through the pipeline with appropriate reagents that elucidate a mechanistic understanding of target biology<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Design, express, purify and characterize soluble and membrane protein targets with enhanced expression and stability enabling functional studies and antibody discovery<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Purify integral membrane proteins/complexes for querying target biology, therapeutic development and structural studies.<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Introduce and lead innovative science enabling publication and external presentations<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext"> <o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext"><b>Qualifications </b>•BS, MS or PhD with a strong foundation in biochemistry, protein purification, structural biology, and at least 12-14+ (BS), 10-12+ (MS) or 4-6+ (PhD) years of post-graduate experience in protein
design and purification <o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Significant research experience as demonstrated by a track record of publications and scientific accomplishments<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Experience with commercially available automated purification systems<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Experience with expression and purification from various host expression systems such as mammalian (HEK/CHO), insect/baculovirus and E.Coli.<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Experience in display technologies (phage, yeast) is a plus<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Demonstrated ability to work with multidisciplinary biologics groups in a fast paced discovery team setting<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Participation in project teams and effective communication with team members throughout the organization.<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext">•Highly developed leadership skills and ability to engage collaborators across the organization<o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext"> <o:p></o:p></p>
<p class="m-8365309022912125717msoplaintext"><b> Equal Opportunity Employer Minorities/Women/Veterans/Disabled</b><o:p></o:p></p>
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<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";text-transform:uppercase">MEDHA J. TOMLINSON, PH.D.</span></b><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Calibri","sans-serif"">Principal Research Scientist</span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#071D49">Abbvie Bioresearch Center</span></b><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Calibri","sans-serif"">Global Biologics – Protein Sciences</span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Calibri","sans-serif"">100 Research Drive</span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:10.0pt;font-family:"Calibri","sans-serif"">Worcester, MA 01605</span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif"">EMAIL </span></b><span style="font-size:10.0pt;font-family:"Calibri","sans-serif";color:#1F497D"> <a href="mailto:Medha.Tomlinson@abbvie.com"><span style="color:black">Medha.Tomlinson@abbvie.com</span></a></span><span style="font-size:11.0pt;font-family:"Calibri","sans-serif""><o:p></o:p></span></p>
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recipient, please note that any other dissemination, distribution, use or copying of this communication is strictly prohibited. Anyone who receives this message in error should notify the sender immediately by telephone or by return e-mail and delete it from
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">Irina I. Serysheva, Ph.D.</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">Associate Professor, Department of Biochemistry and Molecular Biology</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">Director of Structural Biology Imaging Center</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">McGovern Medical School </span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">The University of Texas Health Science Center at Houston</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">6431 Fannin, MSB 6.210, Houston, TX 77030 </span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">Tel.: 713-500-5523 (office); 713-500-6232 (lab)</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">Fax: 713-500-0652</span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">E-mail: <a href="mailto:Irina.I.Serysheva@uth.tmc.edu">Irina.I.Serysheva@uth.tmc.edu</a></span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979"> <a href="mailto:irinas@bcm.edu">irinas@bcm.edu</a></span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">https:/<a href="http://med.uth.edu/bmb/faculty/serysheva-irina/">med.uth.edu/bmb/faculty/serysheva-irina/</a></span><span style="color:black"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Calibri","sans-serif";color:#797979">"Success is the ability to go from one failure to another with no loss of enthusiasm" - Sir Winston Churchill</span><span style="color:black"><o:p></o:p></span></p>
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