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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#254061;mso-style-textfill-fill-color:#254061;mso-style-textfill-fill-alpha:100.0%"><span style="color:windowtext">Well noted Mark.<o:p></o:p></span></span></p>
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<p class="MsoNormal" style="background:white"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#244061">With warm regards, <o:p></o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#244061"><o:p> </o:p></span></p>
<p class="MsoNormal" style="background:white"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#244061">Andreas
<o:p></o:p></span></p>
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<p class="MsoNormal" style="line-height:105%"><b><span style="font-size:14.0pt;line-height:105%;font-family:"Helvetica Neue";color:#595959">Dr. Andreas Holzenburg, FRMS</span></b><span style="font-size:11.0pt;line-height:105%;font-family:"Calibri",sans-serif;color:#1F497D"><o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:105%"><i><span style="font-size:11.0pt;line-height:105%;font-family:"Helvetica Neue";color:#595959">Professor<o:p></o:p></span></i></p>
<p class="MsoNormal" style="line-height:105%"><i><span style="font-size:11.0pt;line-height:105%;font-family:"Helvetica Neue";color:#595959">Medical Education and Academic Affairs
<o:p></o:p></span></i></p>
<p class="MsoNormal" style="line-height:105%"><i><span style="font-size:11.0pt;line-height:105%;font-family:"Helvetica Neue";color:#595959">School of Medicine
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<p class="MsoNormal" style="line-height:105%"><span style="font-size:11.0pt;line-height:105%;font-family:"Helvetica Neue";color:#595959">2102 Treasure Hills Blvd.
<o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:105%"><span style="font-size:11.0pt;line-height:105%;font-family:"Helvetica Neue";color:#595959">Room 3.100<o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:105%"><span style="font-size:11.0pt;line-height:105%;font-family:"Helvetica Neue";color:#595959">Harlingen, TX 78550<i><o:p></o:p></i></span></p>
<p class="MsoNormal" style="line-height:105%"><span style="font-size:11.0pt;line-height:105%;font-family:"Helvetica",sans-serif;color:#595959">956-296-1556 •
</span><u><span style="font-size:11.0pt;line-height:105%;font-family:"Helvetica",sans-serif;color:#0563C1"><a href="mailto:andreas.holzenburg@utrgv.edu"><span style="color:#0563C1">andreas.holzenburg@utrgv.edu</span></a></span></u><span style="font-size:11.0pt;line-height:105%;font-family:"Calibri",sans-serif;color:#1F497D"><o:p></o:p></span></p>
<p class="MsoNormal" style="line-height:105%"><span style="font-size:10.0pt;line-height:105%;font-family:"Helvetica",sans-serif;color:#595959">Brownsville • Edinburg • Harlingen</span><span style="font-size:11.0pt;line-height:105%;font-family:"Calibri",sans-serif;color:#1F497D"><o:p></o:p></span></p>
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<p class="MsoNormal"><span lang="EN-GB" style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D"><a href="https://na01.safelinks.protection.outlook.com/?url=http%3A%2F%2Fascimaging.springeropen.com&data=02%7C01%7Candreas.holzenburg%40utrgv.edu%7C61925b1632724e2dc66e08d5e710ab11%7C990436a687df491c91249afa91f88827%7C0%7C0%7C636668981140529882&sdata=SlfIXZGEQDcenANgJMEOo8rUyVOZm%2Fy0cRrheTvnMpU%3D&reserved=0">http://ascimaging.springeropen.com</a></span><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D"><o:p></o:p></span></p>
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<p class="MsoNormal"><b><i><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D">Nothing ever happened great that wasn’t difficult - Wm. Eugene Powell </span></i></b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:#1F497D"><o:p></o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:windowtext">From:</span></b><span style="font-size:11.0pt;font-family:"Calibri",sans-serif;color:windowtext"> 3dem <3dem-bounces@ncmir.ucsd.edu>
<b>On Behalf Of </b>Mark Yeager<br>
<b>Sent:</b> Saturday, July 28, 2018 11:21 PM<br>
<b>To:</b> 3dem@ncmir.ucsd.edu<br>
<b>Subject:</b> Re: [3dem] History of 3DEM and genealogy page (1968 - 2011)<o:p></o:p></span></p>
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<p class="MsoNormal">-------- Forwarded Message -------- <o:p></o:p></p>
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<p class="MsoNormal">Re: [3dem] History of 3DEM and genealogy page (1968 - 2011)<o:p></o:p></p>
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<p class="MsoNormal" align="right" style="text-align:right"><b>Date: <o:p></o:p></b></p>
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<p class="MsoNormal">Sun, 8 Jul 2018 16:05:17 -0400<o:p></o:p></p>
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<p class="MsoNormal" align="right" style="text-align:right"><b>From: <o:p></o:p></b></p>
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<p class="MsoNormal">Mark Yeager <a href="mailto:my3r@virginia.edu"><my3r@virginia.edu></a><o:p></o:p></p>
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<p class="MsoNormal"><a href="mailto:3dem@ncmir.ucsd.edu">3dem@ncmir.ucsd.edu</a><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif">Dear Martin, Alexis, John, Ardan and Sriram</span><o:p></o:p></p>
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<span style="font-size:10.0pt;font-family:"Arial",sans-serif"> </span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif">Thanks very much for all your effort. Yes, the field is more exciting than ever!</span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif"> </span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif">I thought that folks might be amused to see the attached picture of Nigel, who has always had an affinity for ice and snow.</span><o:p></o:p></p>
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<span style="font-size:10.0pt;font-family:"Arial",sans-serif"> </span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif">Perhaps this was already pointed out, but I noticed that Ernst Ruska wasn't identified in your map as having received a Nobel Prize, which he was awarded at the age of 80. In fact, his Ph.D. thesis in 1933, provided
the conception for magnetic lenses. </span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif"><a href="https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.nobelprize.org%2Fnobel_prizes%2Fphysics%2Flaureates%2F1986%2Fperspectives.html&data=02%7C01%7Candreas.holzenburg%40utrgv.edu%7Cb702dfd52bb24960cf3a08d5f50ad6a4%7C990436a687df491c91249afa91f88827%7C0%7C0%7C636684349297689944&sdata=BDQVbojvOLlYwJRpmeakewsPqQZ2mTArF%2FjhO2Mkxgk%3D&reserved=0">https://www.nobelprize.org/nobel_prizes/physics/laureates/1986/perspectives.html</a></span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif"> </span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif">Ruska's brother Helmut, a physician, 'managed to convince his former medical professor, Richard Siebeck, director of the medical clinic at the Charité Hospital in Berlin, that his brother's invention was worth investing
time and effort into. In an advisory opinion to the industry, dated October 2 1936, and three years after the completion of the prototype electron microscope, Siebeck described how Ruska's electron microscope could be of immense value to him, as it could
<i>advance research into the causes of disease, particularly infectious agents that couldn't be seen with a light microscope, such as those that cause smallpox, chickenpox, measles, mumps and influenza</i>. "Success seems to me so close, that I am ready and
willing to advise on medical research work and to collaborate by making available the resources of my institute," wrote Siebeck.'
</span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif"> </span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif">So it seems that relevance to medical research was the driving force for Siemens to commercialize the electron microscope. It has now come full circle with pharmas establishing cryoEM labs to pursue drug discovery.</span><o:p></o:p></p>
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<o:p> </o:p></p>
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<span style="font-family:"Arial",sans-serif">For some reason I keep seeing the outline of a ribosome in your map. : )</span><o:p></o:p></p>
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<span style="font-size:10.0pt;font-family:"Arial",sans-serif"> </span> <o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif">All best wishes</span><o:p></o:p></p>
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<span style="font-family:"Arial",sans-serif">Mark</span><o:p></o:p></p>
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<span style="font-size:10.0pt;font-family:"Arial",sans-serif"> </span><o:p></o:p></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif">On 6/7/18 1:47 PM, Ardan Patwardhan wrote:<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif">Dear all<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif">We are very pleased to present the History of 3DEM webpage (<a href="https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.ebi.ac.uk%2Fpdbe%2Femdb%2Fgenealogy.html&data=02%7C01%7Candreas.holzenburg%40utrgv.edu%7Cb702dfd52bb24960cf3a08d5f50ad6a4%7C990436a687df491c91249afa91f88827%7C0%7C0%7C636684349297689944&sdata=gZs3ID7FkRbUlhoO2B08%2Frk1Y3w3iTU8LAkBXZ8vrj0%3D&reserved=0">https://www.ebi.ac.uk/pdbe/emdb/genealogy.html</a>)
featuring a dynamic genealogy of the development of the field from 1968-2011. We realize that there are omissions and corrections which need to be made to the genealogy map. Please submit your comments to us and we will endeavor to make the corrections in
a timely fashion.<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif">Best wishes<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif">Martin Kessel (<a href="mailto:martink1937@gmail.com">martink1937@gmail.com</a>)<br>
Hebrew University of Jerusalem and the National Cancer Institute, NIH<br>
<br>
Alexis Rohou (<a href="mailto:a.rohou@gmail.com">a.rohou@gmail.com</a>)<br>
Genentech<br>
<br>
John Henry J. Scott (<a href="mailto:johnhenry.scott@nist.gov">johnhenry.scott@nist.gov</a>)<br>
National Institute of Standards and Technology<br>
<br>
Ardan Patwardhan (<a href="mailto:ardan@ebi.ac.uk">ardan@ebi.ac.uk</a>)<br>
EMBL-EBI<br>
<br>
Sriram Somasundharam (<a href="mailto:sriram@ebi.ac.uk">sriram@ebi.ac.uk</a>)<br>
EMBL-EBI<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif"><br>
<br>
<br>
<o:p></o:p></span></p>
<pre>_______________________________________________<o:p></o:p></pre>
<pre>3dem mailing list<o:p></o:p></pre>
<pre><a href="mailto:3dem@ncmir.ucsd.edu">3dem@ncmir.ucsd.edu</a><o:p></o:p></pre>
<pre><a href="https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fmail.ncmir.ucsd.edu%2Fmailman%2Flistinfo%2F3dem&data=02%7C01%7Candreas.holzenburg%40utrgv.edu%7Cb702dfd52bb24960cf3a08d5f50ad6a4%7C990436a687df491c91249afa91f88827%7C0%7C0%7C636684349297846195&sdata=13pOtFmEXC1QZsQt7Lp91jMsHkUJR84wW0mexizcwQQ%3D&reserved=0">https://mail.ncmir.ucsd.edu/mailman/listinfo/3dem</a><o:p></o:p></pre>
</blockquote>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif"><o:p> </o:p></span></p>
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<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri",sans-serif">--
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<o:p></o:p></span></p>
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<span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">********************************************************************</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">Mark Yeager, M.D., Ph.D.</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">Professor, Department of Molecular Physiology and Biological Physics</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">University of Virginia School of Medicine</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">and</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">Professor, Department of Medicine</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">Division of Cardiovascular Medicine</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">University of Virginia Health System</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif"> </span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">Sheridan G. Snyder Translational Research Building, Rm 320</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">480 Ray C. Hunt Drive</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">Charlottesville, VA 22908</span><o:p></o:p></p>
<p style="margin-top:.1pt"> <o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">Phone: 434-243-4676</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">FAX: 434-243-8271</span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">E-mail:
<a href="mailto:yeager@virginia.edu">yeager@virginia.edu</a></span><o:p></o:p></p>
<p style="margin-top:.1pt"><span style="font-size:12.0pt;font-family:"Helvetica",sans-serif">********************************************************************</span><o:p></o:p></p>
<p style="margin-top:.1pt"> <o:p></o:p></p>
<p style="margin-top:.1pt"> <o:p></o:p></p>
<p style="mso-margin-top-alt:.1pt;margin-right:0in;margin-bottom:.1pt;margin-left:0in">
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If you are not the intended recipient or the person responsible for delivering the e-mail to the intended recipient, you are hereby notified that any dissemination or copying of this e-mail or any of its attachment(s) is strictly prohibited. If you have received
this e-mail in error, please immediately notify the sending individual or entity by e-mail and permanently delete the original e-mail and attachment(s) from your computer system. Thank you for your cooperation.</span><o:p></o:p></p>
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