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<div class="">Dear all,</div>
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<div class="">The research group of Luca Jovine at Karolinska Institutet has an opening for a postdoctoral fellow to study protein complexes involving TGF-beta superfamily coreceptors, with a focus on endoglin/CD105 - a key human glycoprotein involved in hereditary
hemorrhagic telangiectasia type 1 (HHT1), preeclampsia and tumor angiogenesis. Parallel studies are also ongoing on a number of structurally related biological systems mediating fertilization as well as protection from bacterial infection.</div>
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<div class="">For further information about our laboratory and recent examples, please see <a href="http://jovinelab.org/" class="">http://jovinelab.org</a> and:</div>
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<div class=""> Saito et al. Cell Rep. 19(9):1917–28 (2017) [ <a href="http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30636-8" class="">http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30636-8</a> ]<span class="Apple-tab-span" style="white-space: pre;">
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<div class=""> Raj et al. Cell 169(7):1315–26 (2017) [ <a href="http://www.cell.com/cell/fulltext/S0092-8674(17)30594-9" class="">http://www.cell.com/cell/fulltext/S0092-8674(17)30594-9</a> ]</div>
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<div class=""> Bokhove et al. Proc. Natl. Acad. Sci. USA 113(6):1552-7 (2016) [ <a href="http://www.pnas.org/content/113/6/1552.long" class="">http://www.pnas.org/content/113/6/1552.long</a> ]</div>
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<div class="">The Department of Biosciences and Nutrition of Karolinska Institutet has state-of-the-art equipment for protein expression and purification, sample characterization (microscale thermophoresis, SEC-MALS) and in house X-ray/EM data collection (Rigaku
Compact HomeLab with PILATUS 200K detector; <a href="http://ki.se/en/bionut/center-for-high-resolution-electron-microscopy-em" class="">http://ki.se/en/bionut/center-for-high-resolution-electron-microscopy-em</a>). Frequent access to various synchrotron sites,
as well as access to the newly established Cryo-EM Swedish National Facility (<a href="https://www.scilifelab.se/facilities/cryo-em/" class="">https://www.scilifelab.se/facilities/cryo-em/</a>), are also available. With their close integration of academic
and clinical research, KI and the Center for Innovative Medicine (CIMED; <a href="http://cimed.ki.se/" class="">http://cimed.ki.se</a> ) - to which our group also belongs - offer a highly international and collaborative environment for biomedical studies.</div>
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<div class="">Candidates should have (or will be soon awarded) a PhD degree and must have significant experience in studying protein-protein interactions, both biochemically and using either X-ray crystallography or single-particle cryo-EM. Proven experience
with the latter and/or protein expression in eukaryotic cells will be a significant advantage. At least one first author paper in a high quality international peer-reviewed journal, fluency in English (both written and oral), good team spirit and a very strong
personal drive to excel in science are required.</div>
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<div class="">For more information about this position and to submit an application through the KI MyNetwork recruitment system by 3 September, please see:</div>
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<div class=""><span class="Apple-tab-span" style="white-space: pre;"></span> <a href="https://ki.mynetworkglobal.com/en/what:job/jobID:156827" class="">https://ki.mynetworkglobal.com/en/what:job/jobID:156827</a></div>
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<div class="">With best wishes,</div>
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<div class="">Luca</div>
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------------------------------------------------------------------------<br class="">
Luca Jovine, Ph.D.<br class="">
Professor of Structural Biology<br class="">
Karolinska Institutet<br class="">
Department of Biosciences and Nutrition & Center for Innovative Medicine<br class="">
Halsovagen 7, SE-141 83 Huddinge, Sweden<br class="">
Voice: +46.(0)8.524-81136 FAX: +46.(0)8.6081-501<br class="">
E-mail: <a href="mailto:luca.jovine@ki.se" class="">luca.jovine@ki.se</a><br class="">
W3: <a href="http://jovinelab.org/" class="">http://jovinelab.org</a><br class="">
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