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<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif">The MRC LMS & Imperial College is looking for a Cryo-EM research Scientist.
<o:p></o:p></span></b></p>
<p class="MsoNormal"><b><span style="font-family:"Arial",sans-serif"><o:p> </o:p></span></b></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Your main role will be to manage the EM requirements of the institute.<b> </b></span><span style="font-family:"Arial",sans-serif">Electron microscopy has been identified as a key technology at
the <span class="caps">ICL</span>/<span class="caps">LMS</span> to support investigation into epigenetic mechanisms, large molecular machines involved in <span class="caps">DNA</span> transactions and chromosome structure. You will<b>
</b>support research groups in structurally characterising proteins using cryo-EM, particularly by single particle analysis. This is an ideal opportunity to apply cutting edge imaging technologies to investigate mechanisms in chromosome biology, to develop
new technological capabilities and work together with leading research groups.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif"><br>
New EM capacity is currently being developed at the Institute, with a view to enhance and expand this significantly over the next few years. Currently, the <span class="caps">LMS</span> is equipped with a CM200 <span class="caps">FEG</span> transmission cryo-electron
microscope, a fast Tietz 2k camera and a sample preparation suite including a Vitrobot Mark IV. Presently, access to high end microscopes is available through the national facility, an established collaboration with the <span class="caps">LMB</span> and the
Wellcome Trust funded LonCEM consortium.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">This is a full-time, three-year position (HM2017109).<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Informal enquiries may be made to Prof. Christian Speck (<a href="mailto:chris.speck@imperial.ac.uk">chris.speck@imperial.ac.uk</a>)
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">For more details and instructions for application, please visit:
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Job advert: <a href="https://www.nature.com/naturejobs/science/jobs/618201-cryo-em-research-scientist">
Nature Website</a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Application link and job description at Imperial College London:
<a href="https://www4.ad.ic.ac.uk/OA_HTML/OA.jsp?page=/oracle/apps/irc/candidateSelfService/webui/VisVacDispPG&akRegionApplicationId=821&transactionid=1709515351&retainAM=Y&addBreadCrumb=S&p_svid=52020&p_spid=1839539&oapc=7&oas=8TIZ1U5bMbnq2A-XGu0V2A">
IC Website</a><o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Best wishes,<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-family:"Arial",sans-serif">Christian<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:DE">__________________________________________</span></i><i><span style="font-size:12.0pt;mso-fareast-language:DE"><o:p></o:p></span></i></p>
<p class="MsoNormal"><span lang="EN-US" style="mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:DE">Professor Christian Speck, PhD, FRSB<o:p></o:p></span></i></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:DE">Chair in Genome Biochemistry & Molecular Biology</span></i><span style="mso-fareast-language:DE"><o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:DE">Wellcome Trust Investigator</span></i><span style="mso-fareast-language:DE"><o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:DE"><o:p> </o:p></span></i></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE">Imperial College London<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE">Faculty of Medicine<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE">Institute of Clinical Sciences (CRB room 3006)<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE">Hammersmith Hospital Campus<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE">Du Cane Road<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE">London W12 0NN<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE">Tel: 0044 20 8383 3387
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE">Mobile: 0044 796 181 5557<o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE">Skype ID: dna_rep<o:p></o:p></span></p>
<p class="MsoNormal"><span lang="EN-US" style="mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><i><span style="mso-fareast-language:DE">email: <span style="color:blue">
<a href="mailto:christian.speck@imperial.ac.uk"><span style="color:blue;font-style:normal">christian.speck@imperial.ac.uk</span></a></span></span></i><span style="mso-fareast-language:DE"><o:p></o:p></span></p>
<p class="MsoNormal"><i><span style="font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-language:DE">website:
</span></i><span style="font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-language:DE"><a href="http://www.specklab.com/"><i><span style="color:blue">www.specklab.com</span></i></a><i>
<span style="color:red"><o:p></o:p></span></i></span></p>
<p class="MsoNormal"><i><span style="font-size:10.0pt;font-family:"Arial",sans-serif;mso-fareast-language:DE">Imperial College website:</span></i><span style="mso-fareast-language:DE">
<i><a href="http://www.imperial.ac.uk/people/chris.speck"><span style="color:blue">www.imperial.ac.uk/people/chris.speck</span></a></i></span><span style="mso-fareast-language:DE"><o:p></o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:DE"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="mso-fareast-language:EN-GB"><img border="0" width="354" height="111" id="Picture_x0020_1" src="cid:image001.jpg@01D2F3F0.EF2B0400" alt="http://www.wellcome.ac.uk/stellent/groups/corporatesite/@policy_communications/documents/web_document/wtvm050463.jpg"></span><a href="http://www.athenaswan.org.uk/" target="_blank"><span style="color:blue;mso-fareast-language:EN-GB;text-decoration:none"><img border="0" width="168" height="92" id="Picture_x0020_2" src="cid:image002.png@01D2F3F0.EF2B0400" alt="Athena Swan Bronze Award Logo"></span></a><span style="mso-fareast-language:DE"><o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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