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<p>Assistant Professor</p>
<p>Department of Biophysics</p>
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<p>The Structural Biology Laboratory at UT Southwestern Medical Center currently has two openings at the non-tenure track Research Assistant Professor level for highly-motivated individuals who enjoy working in a collaborative, multi-disciplinary setting.</p>
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<p>· Position #1: Cryo-electron microscopist with extensive experience in high resolution single-particle reconstruction, including sample grid preparation, data collection, the use of modern software for particle picking and classification, map generation,
model building and structure validation. Experience in cryo-EM tomography is a plus.</p>
<p>· Position #2: X-ray crystallographer with extensive experience in modern methods of crystallization, data collection using home and synchrotron sources, structure solution via various experimental techniques, refinement and structure validation.</p>
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<p>For both positions, a Ph.D. in biochemistry, chemistry, physics or a related field is required. Facility with related techniques for each position such as cryo-electron microscopy, X-ray crystallography, NMR, small-angle X-ray scattering, isothermal titration
calorimetry, analytical ultracentrifugation and protein expression and purification is highly desirable.</p>
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<p>Job requirements include a significant amount of both formal and informal teaching, and teaching experience is highly desirable. Salary is competitive and commensurate with experience and qualifications.</p>
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<p><strong>About the UT Southwestern Structural Biology Laboratory</strong></p>
<p>The Structural Biology Laboratory (Diana Tomchick, Director) is a platform that allows researchers with different expertise to come together in a collaborative setting and tackle biological problems in a comprehensive way. Our publications are representative
of the success of this strategy: <a href="http://www3.utsouthwestern.edu/sbl/Publications.html">
http://www3.utsouthwestern.edu/sbl/Publications.html</a></p>
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<p>State-of-the-art equipment is currently installed, operational and shared between the members in the Structural Biology community at UT Southwestern. Cryo-EM equipment consists of one 300 kV Titan Krios microscope, one 200 kV Talos Arctica microscope, and
a cryo-Scios DualBeam for cryo-FIB milling. In addition, the Structural Biology Laboratory has a dedicated lab for cryo-EM grid preparation, with an FEI Vitrobot and assorted instruments for sample prep. Computational facilities include a campus high-performance
computing cluster. Crystallographic equipment includes an Art Robbins Gryphon crystallization robot and a Scorpion liquid handling robot, a Jansi UVEX UV microscope, a Rigaku FRE superbright rotating anode X-ray generator with an ACTOR sample mounting robot,
and 30 days of guaranteed synchrotron beam time at Sector 19 of the Advanced Photon Source.</p>
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<p>These facilities are supplemented by a variety of biophysical instruments supporting the study of macromolecules using NMR, CD, dynamic light scattering, analytical ultracentrifugation, stopped-flow kinetics, isothermal titration calorimetry, microscale
thermophoresis and mass spectrometry.</p>
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<p>Applicants should submit a <em>curriculum vita</em> and three letters of reference by
<strong>July 10, 20</strong><strong>17</strong> to Diana Tomchick, Chair, Structural Biology Laboratory Search Committee, U.T. Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-8816. <em>UT Southwestern is an Affirmative Action/Equal Opportunity
Employer.</em><em> </em><em>Women, minorities, veterans and individuals with disabilities are encouraged to apply.</em></p>
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<p>For further inquiries, please contact:</p>
<p>Diana Tomchick</p>
<p>Department of Biophysics, Rm. ND10.214A</p>
<p>UT Southwestern Medical Center</p>
<p>5323 Harry Hines Blvd</p>
<p>Dallas TX 75390-8816</p>
<p>Tel. +1 214 645 6383</p>
<p>Email: <a href="mailto:Diana.Tomchick@UTSouthwestern.edu">Diana.Tomchick@UTSouthwestern.edu</a></p>
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<div class="PlainText">**************************************************<br>
Diana R. Tomchick<br>
Professor<br>
Departments of Biophysics and Biochemistry<br>
University of Texas Southwestern Medical Center<br>
5323 Harry Hines Blvd.<br>
Rm. ND10.214A<br>
Dallas, TX 75390-8816<br>
Diana.Tomchick@UTSouthwestern.edu<br>
(214) 645-6383 (phone)<br>
(214) 645-6353 (fax)</div>
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