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<div>
<div><font face="Calibri,sans-serif">Dear colleagues,</font></div>
<div><span style="font-family: Calibri, sans-serif;">Please see below a job opportunity at FNLCR/Leidos Biomedical Research, Inc.</span></div>
<div><span style="font-family: Calibri, sans-serif;">Best regards,</span></div>
</div>
<div><span style="font-family: Calibri, sans-serif;">Ulrich </span></div>
<div>
<div id="">
<p class="MsoNormal" style="color: rgb(0, 0, 0); font-family: Calibri, sans-serif; font-size: 11pt; margin: 0in 0in 0.0001pt;">
<span style="font-size: 13px; font-family: Calibri;">-------------------------------------------------------------</span></p>
<div>
<div id="">
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: 11pt;"><span style="font-size: 13px;">Ulrich Baxa, PhD</span></p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: 11pt;"><span style="font-size: 13px;">National Cryo-EM Facility</span></p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: 11pt;"><span style="font-size: 13px;">Cancer Research Technology Program</span></p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: 11pt;"><span style="font-size: 13px;">Leidos Biomedical Research, Inc.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: 11pt;"><span style="font-size: 13px;">Frederick National Laboratory for Cancer Research<o:p></o:p></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: 11pt;"><span style="font-size: 13px;">P.O. Box B<o:p></o:p></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: 11pt;"><span style="font-size: 13px;">Frederick, MD 21702<o:p></o:p></span></p>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt; font-size: 11pt;"><br>
</p>
</div>
</div>
<p class="MsoNormal" style="margin: 0in 0in 0.0001pt;"><font face="Calibri,sans-serif"><span style="font-size: 13px;">————————————————</span></font></p>
<p class="MsoNormal" style="color: rgb(0, 0, 0); font-family: Calibri, sans-serif; margin: 0in 0in 0.0001pt;">
<span style="font-size: 13px;"><br>
</span></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;mso-outline-level:1;background:white">
<b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black">Leidos Biomedical Research, Inc.
<o:p></o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;mso-outline-level:1;background:white">
<b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black">CRYO Electron Microscopy Team Lead (NCI)<o:p></o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;mso-outline-level:1;background:white">
<b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black">Position number: 636356<o:p></o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;background:white">
<b><span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black">To apply:
</span></b><a href="http://jobs.leidos.com/ShowJob/Id/1164413/CRYO-Electron-Microscopy-Team-Lead-(NCI)/"><span style="font-size:12.0pt;mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:
Arial">http://jobs.leidos.com/ShowJob/Id/1164413/CRYO-Electron-Microscopy-Team-Lead-(NCI)/</span></a><b><span style="font-size:12.0pt;mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:
Arial;color:black"><span style="mso-spacerun:yes">
</span><o:p></o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;background:white">
<b><span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;mso-outline-level:1;background:white">
<b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black">PROGRAM DESCRIPTION</span></b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black">The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to
accomplish NCI research objectives. The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and also provides dedicated support to NCI’s intramural Center for Cancer Research (CCR) for electron microscopy,
protein characterization, protein expression, optical microscopy and genetics. The Center for Molecular Microscopy (CMM) is a collaborative component located in Frederick, Maryland. The mission of the CMM is to provide CCR Investigators with access to high-resolution
electron microscopy (EM) for molecular and cellular imaging and to develop new techniques and technologies for structural analysis in these areas. CMM currently has two components, Cryo-EM and focused ion beam scanning EM (FIB SEM), and uses both, as well
as related techniques, to collaboratively support CCR research projects. The current recruitment is for the Cryo-EM Team Lead position.<o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black"> <o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;mso-outline-level:1;background:white">
<b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black">JOB DESCRIPTION</span></b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black">The Cryo-EM Team lead will:<o:p></o:p></span></p>
<ul type="disc">
<li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Work collaboratively with investigators in designing and executing cryo-EM projects<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Provide scientific and technical advice to investigators on sample preparation, experimental design, data analysis<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Oversee CMM staff to assure the continuous operation of the Titan Krios microscope; tasks will include loading samples, screening, and performing high-resolution
data collection for single-particle analysis and Cryo-electron tomography;<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Lead projects to develop new techniques relevant to high-resolution Cryo-EM;<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Evaluate Cryo-EM project applications in single particle analyses and tomography, and assist with evaluations of cellular imaging (FIB SEM) project applications;<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
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<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Oversee and track progress for Cryo-EM projects;<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Manage communications with Cryo-EM collaborators;<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Manage maintenance for the Titan Krios and associated instruments (e.g. T12, T20);<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Manage data storage and transfer to collaborators as appropriate;<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Draft communications for submission to the CMM steering committee;<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
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<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Train new CMM personnel and other users in use of the Titan Krios and data collection software as necessary;<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l1 level1 lfo1;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Interact closely and effectively with colleagues within the CMM, including those focused on FIB SEM.<o:p></o:p></span>
</li></ul>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;background:white">
<b><span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;background:white">
<b><span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black"><o:p> </o:p></span></b></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;mso-outline-level:1;background:white">
<b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black">BASIC QUALIFICATIONS</span></b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;background:white">
<b><span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black">To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:</span></b><span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black"><o:p></o:p></span></p>
<ul type="disc">
<li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l0 level1 lfo2;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Possession of a Doctoral degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in Biological
Sciences or related discipline.<o:p></o:p></span> </li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l0 level1 lfo2;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Foreign degrees must be evaluated for U. S. equivalency.<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l0 level1 lfo2;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Minimum of 5 years of experience with Cryo-EM, Cryo-electron tomography, and high resolution single-particle analysis<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l0 level1 lfo2;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Must be detail-oriented and able to manage multiple projects simultaneously<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l0 level1 lfo2;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Excellent written and verbal communication skills<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l0 level1 lfo2;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Able to prepare detailed, concise technical reports, including assisting with publications<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l0 level1 lfo2;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Strong laboratory skills<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l0 level1 lfo2;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Able to work dynamically in a diverse team environment <o:p></o:p></span>
</li></ul>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;mso-outline-level:1;background:white">
<b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black">PREFERRED QUALIFICATIONS</span></b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black"><o:p></o:p></span></p>
<p class="MsoNormal" style="margin-bottom:0in;margin-bottom:.0001pt;line-height:
normal;mso-outline-level:1;background:white">
<b><span style="font-size:12.0pt;
mso-fareast-font-family:"Times New Roman";mso-bidi-font-family:Arial;
color:black">Candidates with these desired skills will be given preferential consideration:</span></b><span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial;color:black"><o:p></o:p></span></p>
<ul type="disc">
<li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l2 level1 lfo3;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Experience with negative stain and other specimen preparation techniques for EM<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l2 level1 lfo3;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Experience with analysis and 3D reconstruction of Cryo-EM data<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l2 level1 lfo3;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Knowledge of scientific computing including Unix shell scripting, as well as Matlab and Python programming languages.<o:p></o:p></span>
</li><li class="MsoNormal" style="color:black;mso-margin-top-alt:auto;mso-margin-bottom-alt:
auto;line-height:normal;mso-list:l2 level1 lfo3;tab-stops:list .5in;
background:white">
<span style="font-size:12.0pt;mso-fareast-font-family:
"Times New Roman";mso-bidi-font-family:Arial">Knowledge of computational aspects of Cryo-EM<o:p></o:p></span>
</li></ul>
<p class="MsoNormal" style="color: rgb(0, 0, 0); font-family: Calibri, sans-serif; font-size: 11pt; margin: 0in 0in 0.0001pt;">
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<w:LsdException Locked="false" Priority="9" SemiHidden="true"
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<w:LsdException Locked="false" Priority="9" SemiHidden="true"
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<w:LsdException Locked="false" Priority="9" SemiHidden="true"
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<w:LsdException Locked="false" Priority="9" SemiHidden="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" Priority="39" SemiHidden="true"
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<w:LsdException Locked="false" Priority="39" SemiHidden="true"
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<w:LsdException Locked="false" Priority="39" SemiHidden="true"
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<w:LsdException Locked="false" Priority="39" SemiHidden="true"
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<w:LsdException Locked="false" Priority="39" SemiHidden="true"
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<w:LsdException Locked="false" Priority="39" SemiHidden="true"
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<w:LsdException Locked="false" Priority="39" SemiHidden="true"
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<w:LsdException Locked="false" Priority="39" SemiHidden="true"
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<w:LsdException Locked="false" Priority="39" SemiHidden="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" Priority="35" SemiHidden="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" SemiHidden="true" UnhideWhenUsed="true"
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<w:LsdException Locked="false" Priority="60" Name="Light Shading Accent 6"/>
<w:LsdException Locked="false" Priority="61" Name="Light List Accent 6"/>
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<w:LsdException Locked="false" Priority="63" Name="Medium Shading 1 Accent 6"/>
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<w:LsdException Locked="false" Priority="72" Name="Colorful List Accent 6"/>
<w:LsdException Locked="false" Priority="73" Name="Colorful Grid Accent 6"/>
<w:LsdException Locked="false" Priority="19" QFormat="true"
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<w:LsdException Locked="false" Priority="21" QFormat="true"
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<w:LsdException Locked="false" Priority="31" QFormat="true"
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<w:LsdException Locked="false" Priority="32" QFormat="true"
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<w:LsdException Locked="false" Priority="33" QFormat="true" Name="Book Title"/>
<w:LsdException Locked="false" Priority="37" SemiHidden="true"
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