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<p><i><span style="font-family: Arial,Helvetica,sans-serif;">dear Colleagues </span>
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<p><i><span style="font-family: Arial,Helvetica,sans-serif;">a reminder: applications close on 31 Jan 2017. </span></i></p>
<p><i><span style="font-family: Arial,Helvetica,sans-serif;">Alessandro</span></i><br>
</p>
 
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<p><span style="font-family:Calibri; color:black"> </span></p>
<p><strong><span style="font-family:Arial">D<span style="color:black">ear colleagues,</span></span></strong></p>
<p><span style="font-family:Calibri; color:black"> </span></p>
<p><strong><span style="font-family:Arial">A<span style="color:black">pplications are open for a </span></span></strong><b><span style="font-family:Arial; color:black; background:white">cryo-electron</span></b><strong><span style="font-family:Arial; color:black"> microscopy
 scientist at the Francis Crick Institute in London to work in the Structural Biology Science Technology Platform.
<br>
</span></strong></p>
<p><strong><span style="font-family:Arial; color:black"><br>
</span></strong></p>
<p><strong><span style="font-family:Arial; color:black">We are looking for a motivated, skilled electron </span></strong><b><span style="font-family:Arial; color:black; background:white">microscopist</span></b><strong><span style="font-family:Arial; color:black"> who
 enjoys interacting with other scientists and will help with single-particle and tomography projects on our two recently</span></strong><strong><span style="font-family:Arial">
<span style="color:black">acquired </span></span></strong><b><span style="font-family:Arial; color:black; background:white">Titan</span></b><strong><span style="font-family:Arial; color:black"> </span></strong><b><span style="font-family:Arial; color:black; background:white">Krios</span></b><strong><span style="font-family:Arial; color:black"> electron
 microscopes. <br>
</span></strong></p>
<p><strong><span style="font-family:Arial; color:black"><br>
</span></strong></p>
<p><strong><span style="font-family:Arial; color:black">Details pasted below and link found here:</span></strong></p>
<p><b style=""><span style="font-family:Arial"><a href="https://goo.gl/XI6NLb" id="LPlnk547283" style="color:blue; text-decoration:underline" previewremoved="true">https://goo.gl/XI6NLb</a></span></b></p>
<p><b style=""><span style="font-family:Arial"><a href="https://goo.gl/XI6NLb" style="color:blue; text-decoration:underline"><br>
</a></span></b></p>
<p><b><span style="font-family:Arial; color:black">For any questions, please contact Peter Rosenthal (Group Leader; </span></b><a href="mailto:peter.rosenthal@crick.ac.uk" style="color:blue; text-decoration:underline"><b><span style="font-family:Arial">peter.rosenthal@crick.ac.uk</span></b></a><b><span style="font-family:Arial; color:black"> ),
 Alessandro Costa (Group Leader; </span></b><a href="mailto:alessandro.costa@crick.ac.uk" style="color:blue; text-decoration:underline"><b><span style="font-family:Arial">alessandro.costa@crick.ac.uk</span></b></a><b><span style="font-family:Arial; color:black"> )
 or Phil Walker (Head, SB STP; </span></b><a href="mailto:philip.walker@crick.ac.uk" style="color:blue; text-decoration:underline"><b><span style="font-family:Arial">philip.walker@crick.ac.uk</span></b></a><b><span style="font-family:Arial; color:black">)</span></b></p>
<p><span style="font-family:Calibri; color:black"> </span></p>
<p><strong><span style="font-family:Arial; color:black">Phil Walker</span></strong></p>
<p><strong><span style="font-family:Arial; color:black">Peter Rosenthal</span></strong></p>
<p><strong><span style="font-family:Arial; color:black">Alessandro Costa</span></strong></p>
<p><span style="font-family:Calibri; color:black"> </span></p>
<p><span style="font-family:Calibri; color:black"> </span></p>
<p><span style="font-family:Calibri; color:black"> </span></p>
<p><strong><span style="font-family:Arial; color:black">Senior Laboratory Research Scientist – </span></strong><b><span style="font-family:Arial; color:black; background:white">Cryo-electron</span></b><span style="font-family:Arial; color:black"> <strong><span style="font-family:Arial">Microscopy
 Scientist</span></strong></span><span style="font-family:Calibri; color:black"><br>
</span><em><span style="font-family:Arial; color:black">Reports to Head, Structural Biology Science Technology Platform</span></em></p>
<p><span style="font-family:Arial; color:black">Salary: Competitive with benefits, subject to skills and experience</span></p>
<p><em><span style="font-family:Arial; color:black">This is a 5 year fixed term position on Crick Terms and Conditions of Employment. There are excellent opportunities for career advancement</span></em><span style="font-family:Arial; color:black">.</span></p>
<p><span style="font-family:Arial; color:black"><br>
</span></p>
<p><strong><span style="font-family:Arial; color:black">SUMMARY</span></strong></p>
<p><span style="font-family:Arial; color:black">The Francis Crick Institute seeks to recruit a <span style="background:white">cryo-electron</span> microscopy (cryo-EM) scientist to support single-particle and tomography projects.</span></p>
<p><span style="font-family:Arial; color:black">The research scientist will be appointed to the Structural Biology Science Technology Platform (SB STP), which supports the Crick in the areas of protein science (expression and purification), biophysics, X-ray
 crystallography, cryo-EM and related areas.</span></p>
<p><span style="font-family:Arial; color:black">The post-holder will build on existing strengths at the Crick Institute in cryo-EM by interacting with members of the technology platform, research groups in cryo-EM, and other structural biology laboratories.
 There are excellent opportunities for career advancement.</span></p>
<p><span style="font-family:Arial; color:black">The Francis Crick Institute is building a state-of-the-art facility for electron microscopy and computation and the post will consolidate excellence in these areas. Two FEI <span style="background:white">Titan</span> <span style="background:white">Krios</span> microscopes
 have recently been purchased and the installation and commissioning of the first of these should be completed in 2016.</span></p>
<p><span style="font-family:Arial; color:black">There are excellent facilities for computing and expertise in experimental and computational aspects of cryoEM being developed through the structural biology platform.</span></p>
<p><span style="font-family:Arial; color:black"><br>
</span></p>
<p><b><span style="font-family:Arial; color:black">KEY<strong><span style="font-family:Arial"> </span></strong>RESPONSIBILITIES</span></b></p>
<p><span style="font-family:Arial; color:black">These include but not limited to; </span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Support a range of cryo-EM research activities through interaction with Crick scientists including cryo-EM scientists and other structural biologists interested in cryo-EM.</span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Contribute to management and maintenance of high-end <span style="background:white">cryo-electron</span> microscopes</span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Support experimental design including sample preparation and imaging of biological specimens.
</span><span style="font-family:Calibri; color:black"><br>
</span></p>
<p><span style="font-family:Calibri; color:black"></span><span style="font-family:Arial; color:black">* Provide expertise and support in computational image analysis.</span><span style="font-family:Arial; color:black"><br>
</span></p>
<p><span style="font-family:Arial; color:black">* Provide training in both experimental and computational aspects of cryo-EM.</span>
</p>
<p><span style="font-family:Arial; color:black"><br>
</span></p>
<p><b><span style="font-family:Arial; color:black">ABOUT<strong><span style="font-family:Arial"> US</span></strong></span></b></p>
<p><span style="font-family:Arial; color:black">The Francis Crick Institute (the Crick) is a partnership between the Medical Research Council (MRC), Cancer Research UK (CRUK), the Wellcome Trust, University College London (UCL), Imperial College London and
 King’s College London. It is a registered charity whose purpose is to conduct biomedical research into all aspects of human health and disease.</span></p>
<p><span style="font-family:Arial; color:black">The institute aspires to be a world-leading centre of biomedical research and innovation. It will promote connections between researchers and disciplines and between academic institutions, healthcare organisations
 and businesses. Dedicated to research excellence, the institute will have the scale, vision and expertise to tackle the most challenging scientific questions underpinning health and disease. It will be world-class with a strong national role — training scientists
 and developing ideas for public good.</span></p>
<p><span style="font-family:Arial; color:black"><br>
</span></p>
<p><b><span style="font-family:Arial; color:black">KEY<strong><span style="font-family:Arial"> </span></strong>EXPERIENCE<strong><span style="font-family:Arial"> </span></strong>AND<strong><span style="font-family:Arial"> </span></strong>COMPETENCIES</span></b></p>
<p><span style="font-family:Arial; color:black">The post holder should embody and demonstrate our core Crick values: Bold, Imaginative, Open, Dynamic and Collegial, in addition to the following:</span></p>
<p><span style="font-family:Arial; color:black"><br>
</span></p>
<p><strong><span style="font-family:Arial; color:black">Essential</span></strong><span style="font-family:Calibri; color:black"></span><span style="font-family:Arial; color:black"><br>
</span></p>
<p><span style="font-family:Arial; color:black">* A higher degree in biological, physical, or engineering sciences. </span><span style="font-family:Calibri; color:black"></span><span style="font-family:Arial; color:black"><br>
</span></p>
<p><span style="font-family:Arial; color:black">* Research experience and expertise in electron microscopy.</span><span style="font-family:Calibri; color:black"></span><span style="font-family:Arial; color:black"><br>
</span></p>
<p><span style="font-family:Arial; color:black">* Specialist knowledge of <span style="background:white">cryo-electron</span> microscope operation and high-resolution data collection.</span><span style="font-family:Calibri; color:black"></span><span style="font-family:Arial; color:black"><br>
</span></p>
<p><span style="font-family:Arial; color:black">* Proven track record in three-dimensional electron microscopy.</span><span style="font-family:Calibri; color:black"></span><span style="font-family:Arial; color:black"><br>
</span></p>
<p><span style="font-family:Arial; color:black">* Excellent communication skills within a research environment, building highly effective working relationships with scientists and support staff.</span><span style="font-family:Calibri; color:black"></span><span style="font-family:Arial; color:black"><br>
</span></p>
<p><span style="font-family:Arial; color:black">* Plan time efficiently and be able to work both independently and in a team setting.</span><span style="font-family:Calibri; color:black"></span></p>
<p><span style="font-family:Calibri; color:black"><br>
</span></p>
<p><span style="font-family:Calibri; color:black"></span><strong><span style="font-family:Arial; color:black">Desirable</span></strong><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* PhD in Structural Biology or related areas.</span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Experience in data analysis single particle images and/or tomography data.</span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Experience with field emission gun microscopes and direct electron detectors.</span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Postdoctoral experience in conducting cutting-edge research in cryo-EM.</span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Authorship in peer-reviewed publications in internationally recognized scientific journals.</span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Specialist knowledge of cryo-EM reconstruction software. </span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Knowledge of scientific computing including Unix shell scripting, Matlab, Python, programming languages.</span><span style="font-family:Calibri; color:black"><br>
</span><span style="font-family:Arial; color:black">* Flexible working practice.</span></p>
<p><span style="font-size:11.0pt; font-family:Calibri"> </span></p>
<p><span style="font-family:Arial; color:black">For any questions, please contact us on </span><a href="mailto:jobs@crick.ac.uk" style="color:blue; text-decoration:underline"><span style="font-family:Arial">jobs@crick.ac.uk</span></a><span style="font-family:Arial; color:black">,
 Peter Rosenthal (Group Leader; </span><a href="mailto:peter.rosenthal@crick.ac.uk" style="color:blue; text-decoration:underline"><span style="font-family:Arial">peter.rosenthal@crick.ac.uk</span></a><span style="font-family:Arial; color:black"> ), Alessandro
 Costa (Group Leader; </span><a href="mailto:alessandro.costa@crick.ac.uk" style="color:blue; text-decoration:underline"><span style="font-family:Arial">alessandro.costa@crick.ac.uk</span></a><span style="font-family:Arial; color:black"> ) or Phil Walker (Head,
 SB STP; </span><a href="mailto:philip.walker@crick.ac.uk" style="color:blue; text-decoration:underline"><span style="font-family:Arial">philip.walker@crick.ac.uk</span></a><span style="font-family:Arial; color:black">)</span></p>
<p><span style="font-family:Arial; color:black">Please note: All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.</span></p>
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The Francis Crick Institute Limited is a registered charity in England and Wales no. 1140062 and a company registered in England and Wales no. 06885462, with its registered office at 1 Midland Road London NW1 1AT</p>
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