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<p class="MsoNormal"
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style="font-size:12.0pt; font-family:"Times New
Roman",serif;mso-fareast-font-family:"Times New
Roman"; mso-fareast-language:EN-GB">Dear All,<o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;
text-align:justify;line-height:normal"><span
style="font-size:12.0pt; font-family:"Times New
Roman",serif;mso-fareast-font-family:"Times New
Roman"; mso-fareast-language:EN-GB">After six successful
schools in this bi-annual series, we are happy to announce: <o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;
text-align:justify;line-height:normal"><b><span
style="font-size:12.0pt; font-family:"Times New
Roman",serif;mso-fareast-font-family:"Times New
Roman"; mso-fareast-language:EN-GB">The Seventh Brazil
School for Single Particle Cryo-EM (11 - 23 August 2016)</span></b><span
style="font-size:12.0pt; font-family:"Times New
Roman",serif;mso-fareast-font-family:"Times New
Roman"; mso-fareast-language:EN-GB"><o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;
text-align:justify;line-height:normal"><span
style="font-size:12.0pt; font-family:"Times New
Roman",serif;mso-fareast-font-family:"Times New
Roman"; mso-fareast-language:EN-GB">This single-particle
data processing school is an intensive hands-on
course/workshop, in which theory and practice are
intertwined. The spectrum of topics covered suits attendees
who are new to the field as well as those for whom the
technique is already of growing importance in their research
and wish to acquire an in-depth understanding of the
methodology. Topics range from data collection and
three-dimensional reconstruction techniques to the final
interpretation of the cryo-EM maps by fitting of X-ray
structures or fitting de-novo atomic co-ordinates. Especially
the last days of the meeting will be devoted to advanced
topics such as: movie-processing, 3D random-startup, dealing
with heterogeneous data sets ("4D" cryo-EM), high-resolution
refinements (~3A) and validation of cryo-EM results.<o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;
text-align:justify;line-height:normal"><span
style="font-size:12.0pt; font-family:"Times New
Roman",serif;mso-fareast-font-family:"Times New
Roman"; mso-fareast-language:EN-GB">The attendees are
expected to bring along a modern notebook computer onto which
all necessary software will be installed. Most processing will
take place in the context of the IMAGIC-4D software system but
other software packages such as FREALIGN, COOT and CHIMERA
will also be used. Cryo-EM data sets will be distributed for
processing during the course. The participants may bring their
own data sets for processing and discussion.<o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;
text-align:justify;line-height:normal"><span
style="font-size:12.0pt; font-family:"Times New
Roman",serif;mso-fareast-font-family:"Times New
Roman"; mso-fareast-language:EN-GB">For the latest
information and registration: </span><a
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style="font-size:12.0pt;font-family:"Times New
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Roman";color:blue;mso-fareast-language:EN-GB"></span></a><a
moz-do-not-send="true" class="moz-txt-link-abbreviated"
href="http://www.single-particles.org/school/"><a class="moz-txt-link-abbreviated" href="http://www.single-particles.org/school/">www.single-particles.org/school/</a></a><span
style="font-size:12.0pt;font-family:"Times New
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<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;
text-align:justify;line-height:normal"><span
style="font-size:12.0pt; font-family:"Times New
Roman",serif;mso-fareast-font-family:"Times New
Roman"; mso-fareast-language:EN-GB">Kind regards,<o:p></o:p></span></p>
<p class="MsoNormal"
style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;
text-align:justify;line-height:normal"><span
style="font-size:12.0pt; font-family:"Times New
Roman",serif;mso-fareast-font-family:"Times New
Roman"; mso-fareast-language:EN-GB">Marin van Heel <o:p></o:p></span></p>
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