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font-family:"Times New Roman"'><span style='mso-element:field-begin'></span><span
style="mso-spacerun:yes"> </span>ADDIN EN.CITE <EndNote><Cite><Author>DiMaio</Author><Year>2015</Year><RecNum>2931</RecNum><DisplayText>(DiMaio
et al., 2015a; DiMaio et al.,
2015b)</DisplayText><record><rec-number>2931</rec-number><foreign-keys><key
app="EN" db-id="0fxs9s929at2aae0psevsezl2rzw5w5stp95" timestamp="1429705371">2931</key></foreign-keys><ref-type
name="Journal
Article">17</ref-type><contributors><authors><author>DiMaio,
F.</author><author>Yu, X.</author><author>Rensen,
E.</author><author>Krupovic,
M.</author><author>Prangishvili, D.</author><author>Egelman,
E.H.</author></authors></contributors><titles><title>A
Virus that Infects a Hyperthermophile Encapsidates A-Form
DNA</title><secondary-title>Science</secondary-title></titles><periodical><full-title>Science</full-title></periodical><pages>914-917</pages><volume>348</volume><section>914</section><dates><year>2015</year></dates><urls></urls></record></Cite><Cite><Author>DiMaio</Author><Year>2015</Year><RecNum>2951</RecNum><record><rec-number>2951</rec-number><foreign-keys><key
app="EN" db-id="0fxs9s929at2aae0psevsezl2rzw5w5stp95"
timestamp="1432646037">2951</key></foreign-keys><ref-type
name="Journal
Article">17</ref-type><contributors><authors><author>DiMaio,
F.</author><author>Chen, C.C.</author><author>Yu,
X.</author><author>Frenz, B.</author><author>Hsu, Y.
H.</author><author>Lin, N. S.</author><author>Egelman,
E.H.</author></authors></contributors><titles><title>The
molecular basis for flexibility in the flexible filamentous plant
viruses</title><secondary-title>Nature Structural & Molecular
Biology</secondary-title></titles><periodical><full-title>Nature
Structural & Molecular Biology</full-title><abbr-1>Nat
Struct Mol
Biol</abbr-1></periodical><pages>642-4</pages><volume>22</volume><section>642</section><dates><year>2015</year></dates><urls></urls></record></Cite></EndNote><span
style='mso-element:field-separator'></span></span><![endif]--><!--[if supportFields]><span
style='font-size:10.0pt;font-family:"Times New Roman"'><span style='mso-element:
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style='font-size:10.0pt;font-family:"Times New Roman"'><span style='mso-element:
field-begin'></span><span style="mso-spacerun:yes"> </span>ADDIN EN.CITE <span
style='mso-element:field-begin'></span><span
style="mso-spacerun:yes"> </span>ADDIN EN.CITE.DATA <![if gte mso 9]><xml>
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style='font-size:10.0pt;font-family:"Times New Roman"'><span style='mso-element:
field-begin'></span><span style="mso-spacerun:yes"> </span>ADDIN EN.CITE
<EndNote><Cite><Author>Egelman</Author><Year>2015</Year><RecNum>2896</RecNum><DisplayText>(Egelman
et al.,
2015)</DisplayText><record><rec-number>2896</rec-number><foreign-keys><key
app="EN" db-id="0fxs9s929at2aae0psevsezl2rzw5w5stp95"
timestamp="1421854587">2896</key></foreign-keys><ref-type
name="Journal Article">17</ref-type><contributors><authors><author>Egelman,
E.H.</author><author>Xu, C.</author><author>DiMaio,
F.</author><author>Magnotti, E.</author><author>Modlin,
C.</author><author>Yu, X.</author><author>Wright,
E.</author><author>Baker,
D.</author><author>Conticello, V. P.</author></authors></contributors><titles><title>Structural
plasticity of helical nanotubes based on coiled-coil
assemblies</title><secondary-title>Structure</secondary-title></titles><periodical><full-title>Structure</full-title></periodical><pages>280-9</pages><volume>23</volume><number>2</number><section>280</section><dates><year>2015</year></dates><urls></urls></record></Cite></EndNote><span
style='mso-element:field-separator'></span></span><![endif]--><!--[if supportFields]><span
style='font-size:10.0pt;font-family:"Times New Roman"'><span style='mso-element:
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style='font-size:10.0pt;font-family:"Times New Roman"'><span style='mso-element:
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font-family:"Times New Roman"'><span style='mso-element:field-end'></span></span><![endif]--><b>Opportunities
in Cryo-EM
of Protein and Nucleoprotein Polymers at the University of
Virginia.</b><br>
The Egelman lab has
developed the main method (IHRSR) that is now being used around
the world for
reconstructing helical polymers at high resolution. Current
projects in the
Egelman lab include the application and further development of
these methods to
helical viruses (DiMaio et al., 2015a; DiMaio et al., 2015b),
bacterial secretion systems (Kudryashev et al., 2015)<!--[if gte mso 9]><xml>
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</xml><![endif]-->. A full publication
list can be found at <a class="moz-txt-link-freetext" href="http://people.virginia.edu/~ehe2n">http://people.virginia.edu/~ehe2n</a>. The
facilities are
exceptional, and include a Titan Krios equipped with a Falcon II
direct
electron detector. If interested please contact Edward Egelman at
<a class="moz-txt-link-abbreviated" href="mailto:egelman@virginia.edu">egelman@virginia.edu</a>.</p>
<p class="MsoNormal"> </p>
<p class="EndNoteBibliographyTitle"><!--[if supportFields]><span
style='font-size:10.0pt;font-family:"Times New Roman"'><span style='mso-element:
field-begin'></span><span style="mso-spacerun:yes"> </span>ADDIN EN.REFLIST <span
style='mso-element:field-separator'></span></span><![endif]--></p>
<p class="EndNoteBibliography">DiMaio, F., Chen, C.C., Yu, X.,
Frenz, B., Hsu, Y.H., Lin,
N.S., and Egelman, E.H. (2015a). The molecular basis for
flexibility in the
flexible filamentous plant viruses. Nat Struct Mol Biol 22,
642-644.</p>
<p class="EndNoteBibliography"> </p>
<p class="EndNoteBibliography">DiMaio, F., Yu, X., Rensen, E.,
Krupovic, M., Prangishvili,
D., and Egelman, E.H. (2015b). A Virus that Infects a
Hyperthermophile
Encapsidates A-Form DNA. Science 348,
914-917.</p>
<p class="EndNoteBibliography"> </p>
<p class="EndNoteBibliography">Egelman, E.H., Xu, C., DiMaio, F.,
Magnotti, E., Modlin, C.,
Yu, X., Wright, E., Baker, D., and Conticello, V.P. (2015).
Structural
plasticity of helical nanotubes based on coiled-coil assemblies.
Structure 23, 280-289.</p>
<p class="EndNoteBibliography"> </p>
<p class="EndNoteBibliography">Kudryashev, M., Wang, R.Y.,
Brackmann, M., Scherer, S.,
Maier, T., Baker, D., DiMaio, F., Stahlberg, H., Egelman, E.H.,
and Basler, M.
(2015). Structure of the Type VI Secretion System Contractile
Sheath. Cell 160, 952-962.</p>
<p class="EndNoteBibliography"> </p>
<p class="EndNoteBibliography">Lu, A., Magupalli, V.G., Ruan, J.,
Yin, Q., Atianand, M.K.,
Vos, M.R., Schroder, G.F., Fitzgerald, K.A., Wu, H., and Egelman,
E.H. (2014).
Unified Polymerization Mechanism for the Assembly of ASC-Dependent
Inflammasomes. Cell 156, 1193-1206.<span
style="font-size:10.0pt;font-family:"Times New Roman";
mso-no-proof:yes"><o:p></o:p></span></p>
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<p class="MsoNormal">Edward H. Egelman, Ph.D.<o:p></o:p></p>
<p class="MsoNormal">Professor<o:p></o:p></p>
<p class="MsoNormal">Dept. of Biochemistry and Molecular
Genetics<o:p></o:p></p>
<p class="MsoNormal">University of Virginia<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">President<o:p></o:p></p>
<p class="MsoNormal">Biophysical Society<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal">phone: 434-924-8210<o:p></o:p></p>
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<p class="MsoNormal"><a class="moz-txt-link-abbreviated" href="mailto:egelman@virginia.edu">egelman@virginia.edu</a><o:p></o:p></p>
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