<html><head><meta http-equiv="Content-Type" content="text/html charset=windows-1252"><meta http-equiv="Content-Type" content="text/html charset=windows-1252"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space;" class="">Hi All,<div class="">We are pleased to officially announce the 6th Biennial NCMI Workshop on Single particle reconstruction, Structural Variability and Modeling to be followed immediately by a 1 day Symposium on CryoEM, in celebration of the 30th Anniversary of the National Center for Macromolecular Imaging.</div><div class=""><br class=""></div><div class="">October 30 - November 2, 2015</div><div class="">and November 3, 2015</div><div class=""><br class=""></div><div class="">The two events are separate, so if you plan to attend both, please remember to register for both:</div><div class=""><a href="http://ncmi.bcm.edu/ncmi/events/workshops/workshops_145" class="">http://ncmi.bcm.edu/ncmi/events/workshops/workshops_145</a></div><div class=""><a href="http://ncmi.bcm.edu/ncmi/events/workshops/workshops_146" class="">http://ncmi.bcm.edu/ncmi/events/workshops/workshops_146</a></div><div class=""><br class=""></div>Thanks to the generosity of our sponsors, both events are completely free (including several meals) but you will be responsible for your own travel/lodging.<br class=""><br class=""><font size="4" class="">The workshop will begin on day 1 with introductory talks
and a brand new EMAN2.11 tutorial. Days 2 and 3 will be devoted to the issue of
both compositional and conformational heterogeneity, from multiple
perspectives, examining the approaches used in 4 different software
packages: Steve Ludtke (EMAN2.1), Sjors Scheres (Relion), Niko
Grigorieff (Frealign) and Pawel Penczek (Sparx). While variability is
often one of the greatest barriers to high resolution structure
determination, it also represents a great opportunity to learn more
about how complex macromolecular machines function in solution. The
final day of the workshop will be devoted to modeling across all resolution
ranges, from low resolution docking to de-novo model building at high
resolution, using a variety of different software tools.</font><br class=""><br class="">This workshop has been very popular in the past, so we encourage you to register as early as possible. There are a number of changes since our last workshop, so please read the details on the website(s) referenced above. Please address any questions to <a href="mailto:sludtke@bcm.edu" class="">sludtke@bcm.edu</a> (workshop content and general questions) or Connie Wallace <<a href="mailto:cwallace@bcm.edu" class="">cwallace@bcm.edu</a>> (questions about site, lodging, travel).<br class=""><br class=""><div apple-content-edited="true" class="">
<div style="color: rgb(0, 0, 0); font-family: Helvetica; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: normal; line-height: normal; orphans: 2; text-align: -webkit-auto; text-indent: 0px; text-transform: none; white-space: normal; widows: 2; word-spacing: 0px; -webkit-text-size-adjust: auto; -webkit-text-stroke-width: 0px; word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; " class=""><span class="Apple-style-span" style="border-collapse: separate; font-family: Courier; font-size: 11px; border-spacing: 0px;"><div style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; " class=""><div class=""><div class=""><div class=""><div class="">----------------------------------------------------------------------------<br class="">Steven Ludtke, Ph.D.<br class="">Professor, Dept. of Biochemistry and Mol. Biol. Those who do</div><div class="">Co-Director National Center For Macromolecular Imaging<span class="Apple-tab-span" style="white-space: pre; "> </span> ARE</div><div class="">Baylor College of Medicine The converse<br class=""><a href="mailto:sludtke@bcm.edu" class="">sludtke@bcm.edu</a> -or- <a href="mailto:stevel@alumni.caltech.edu" class="">stevel@alumni.caltech.edu</a> also applies<br class=""><a href="http://ncmi.bcm.edu/~stevel" class="">http://ncmi.bcm.edu/~stevel</a><br class=""></div></div></div></div></div></span></div>
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