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    Hi,<br>
      But for those who are paranoid (and there really may be people out
    to get you, so perhaps the paranoia is warranted) the main danger in
    the review process is that your conclusions become known, perhaps to
    your competitors. So I do not view the map as more important than
    the conclusions, which are no longer secret. But while the reviewers
    are anonymous to the authors, they are certainly not anonymous to
    the editor. So if one suspects that material was compromised during
    the review process, you can simply write to the editor of the
    journal and say that you suspect Dr. X of using your results, and it
    is important to determine whether Dr. X was one of the reviewers.
    Almost all editors would take this extremely seriously, as it goes
    to the foundation of peer-review. I speak as a former editor of a
    journal, where I did receive such inquiries (and in every instance,
    Dr. X was not one of the reviewers!).<br>
    Regards,<br>
    Ed<br>
    <br>
    <div class="moz-cite-prefix">On 4/30/15 5:48 PM, Mike Strauss wrote:<br>
    </div>
    <blockquote
      cite="mid:274BC568-E0CE-4D8B-B637-1CE49F4F5590@crystal.harvard.edu"
      type="cite">
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      Hi,
      <div class=""><br class="">
      </div>
      <div class="">Unlike Ed, I do understand the basis for the
        paranoia, but I do not see a sensible way around it.  Our system
        is currently based on anonymous peer review, be that good or
        ill.  As such, if we expect thorough, honest, accurate, and
        ultimately helpful reviews, it only makes sense that the
        reviewer can look at the maps to assess the claims made, and to
        suss out potential errors in processing or methodology.
         Ultimately they will have to be deposited regardless.  I don’t
        see how you can avoid trusting the reviewers to behave
        honourably.</div>
      <div class=""><br class="">
      </div>
      <div class="">Having said that, perhaps we should consider
        implementing a system where reviewers are de-anonymised in the
        event of a controversy (ie. your paper is scooped after a 4
        month review process).</div>
      <div class=""><br class="">
      </div>
      <div class="">mike</div>
      <div class=""><br class="">
        <div>
          <blockquote type="cite" class="">
            <div class="">On Apr 30, 2015, at 5:01 PM, Edward Egelman
              <<a moz-do-not-send="true"
                href="mailto:egelman@virginia.edu" class="">egelman@virginia.edu</a>>
              wrote:</div>
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              <div bgcolor="#FFFFFF" text="#000000" class=""> Hi,<br
                  class="">
                  First, let me say that I was not the reviewer! Second,
                I recently spoke at an NIH workshop on reproducibility
                in structural biology:<br class="">
                <a moz-do-not-send="true" class="moz-txt-link-freetext"
                  href="http://wals.od.nih.gov/reproducibility/">http://wals.od.nih.gov/reproducibility/</a><br
                  class="">
                and making maps and models available to reviewers BEFORE
                publication, and not AFTER, was one of my
                recommendations. I gave several examples of papers in
                high profile journals that would never have been
                published had reviewers actually compared the maps and
                models during review. I do not understand the basis for
                the paranoia.<br class="">
                Regards,<br class="">
                Ed<br class="">
                <br class="">
                <div class="moz-cite-prefix">On 4/30/15 4:19 PM,
                  Friedrich Foerster wrote:<br class="">
                </div>
                <blockquote
cite="mid:CALtyCEi3HpeKiciMXgV59T2XZT3TsfLyfCMn4qg-vXffCvZ=6w@mail.gmail.com"
                  type="cite" class="">
                  <div dir="ltr" class="">
                    <div class="">
                      <div class="">
                        <div class="">
                          <div class="">
                            <div class="">dear colleagues,<br class="">
                              <br class="">
                            </div>
                            i would be interested in experiences /
                            suggestions / views of others in the field
                            on  the following issue that may be of
                            interest to many of us:<br class="">
                          </div>
                          the editor of our manuscript forwarded the
                          request of a peer-reviewer to access the
                          cryo-em map of our beloved complex. this has
                          never happened to us, but to our surprise the
                          editor did not consider the request to be
                          unusual.<br class="">
                          of course, we share the point that the map
                          would be of great help in judging the
                          interpretation of the data. however, we also
                          feel very uncomfortable sending the condensed
                          result of lengthy research to an anonymous
                          colleague, who could theoretically make
                          considerable misuse of it. nevertheless, the
                          policy of the journal seems to let us little
                          choice: "<font class="" size="2">Supporting
                            data must be made available to editors and
                            peer</font><font class="" size="2">-</font><font
                            class="" size="2">reviewers at the time of</font><font
                            class="" size="2"> submission for the
                            purposes of evaluating the manuscript.</font><font
                            class="" size="2"> Peer</font><font class=""
                            size="2">-</font><font class="" size="2">reviewers</font><font
                            class="" size="2"> may be asked</font><font
                            class="" size="2"> to comment on the terms
                            of access to materials, methods and/or data
                            sets</font><font class="" size="2">"</font>.<br
                            class="">
                        </div>
                        in any case we would be curious whether others
                        indeed got similar requests and how they dealt
                        with it. a good solution for (paranoid?) people
                        like us could be a good web-based viewer that
                        lets others view our map, but i would not know
                        of such a tool.<br class="">
                        <br class="">
                      </div>
                      Thanks <br class="">
                      <br class="">
                    </div>
                    Friedrich<br class="" clear="all">
                    <div class="">
                      <div class="">
                        <div class="">
                          <div class="">
                            <div class="">
                              <div class="">
                                <div class="">
                                  <div class=""><br class="">
                                    -- <br class="">
                                    <div class="gmail_signature">Dr.
                                      Friedrich Foerster<br class="">
                                      Max-Planck Institut fuer Biochemie<br
                                        class="">
                                      Am Klopferspitz 18<br class="">
                                      D-82152 Martinsried<br class="">
                                      <br class="">
                                      Tel: +49 89 8578 2632<br class="">
                                      Fax: +49 89 8578 2641<br class="">
                                      <br class="">
                                      <a moz-do-not-send="true"
                                        href="http://www.biochem.mpg.de/foerster"
                                        target="_blank" class="">www.biochem.mpg.de/foerster</a><br
                                        class="">
                                    </div>
                                    <br class="">
                                  </div>
                                </div>
                              </div>
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                  <pre class="" wrap="">_______________________________________________
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                </blockquote>
                <br class="">
                <pre class="moz-signature" cols="72">-- 
Edward H. Egelman, Ph.D.
Professor
Dept. of Biochemistry and Molecular Genetics
University of Virginia

President
Biophysical Society

phone: 434-924-8210
fax: 434-924-5069
<a moz-do-not-send="true" class="moz-txt-link-abbreviated" href="mailto:egelman@virginia.edu">egelman@virginia.edu</a>
<a moz-do-not-send="true" class="moz-txt-link-freetext" href="http://www.people.virginia.edu/%7Eehe2n">http://www.people.virginia.edu/~ehe2n</a>
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                class="">
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                href="mailto:3dem@ncmir.ucsd.edu" class="">3dem@ncmir.ucsd.edu</a><br
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            </div>
          </blockquote>
        </div>
        <br class="">
      </div>
    </blockquote>
    <br>
    <pre class="moz-signature" cols="72">-- 
Edward H. Egelman, Ph.D.
Professor
Dept. of Biochemistry and Molecular Genetics
University of Virginia

President
Biophysical Society

phone: 434-924-8210
fax: 434-924-5069
<a class="moz-txt-link-abbreviated" href="mailto:egelman@virginia.edu">egelman@virginia.edu</a>
<a class="moz-txt-link-freetext" href="http://www.people.virginia.edu/~ehe2n">http://www.people.virginia.edu/~ehe2n</a>
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