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<!--StartFragment--><p class="MsoNormal" style="text-align:justify"><span class="Apple-style-span" style="color: rgb(26, 26, 26); line-height: 18px; ">Postdoc position in the
group of Elena Conti, at the Max Planck Institute of Biochemistry (Munich,
Germany).</span></p><p class="MsoNormal" style="text-align:justify"><font class="Apple-style-span" color="#1a1a1a"><p class="MsoNormal" style="text-align:justify;line-height:150%"><span style="mso-bidi-font-family:Helvetica;color:#1A1A1A">Our group is interested in
the molecular mechanisms used by eukaryotic cells to detect and eliminate defective
or unnecessary RNA molecules. </span>We study the macromolecular complexes that
underpin RNA quality control and degradation processes, with the aim to elucidate
how they function at the molecular and chemical level. To this end, we use
biochemical, biophysical and structural biology approaches<span style="mso-bidi-font-family:Helvetica;color:#1A1A1A"> (see recent examples in
Benda et al., Mol Cell 2014; Schaefer et al., NSMB 2014; Makino et al., Nature
2013; Halbach et al., Cell 2013; Sharif and Conti, Cell Rep 2013).</span></p><p class="MsoNormal" style="text-align:justify;line-height:150%"><span style="mso-bidi-font-family:Helvetica;color:#1A1A1A">We are looking for a
candidate who has experience in single-particle cryo-EM and who is interested
to work at the interface of different structural biology techniques. The successful
candidate will reconstitute, purify and biochemically characterize a macromolecular complex (with protocols available in the lab) and will then use EM
(either alone or in combination with X-ray crystallography and mass-spec
crosslinking) to elucidate its high-resolution structure. In addition to
his/her primary project, there is the possibility for the candidate to
collaborate with other lab members on different projects .</span></p><p class="MsoNormal" style="text-align:justify;line-height:150%;mso-pagination:
none;mso-layout-grid-align:none;text-autospace:none"><span style="mso-bidi-font-family:
Helvetica;color:#1A1A1A">The candidate will be embedded in an international and
multidisciplinary environment. Our lab is adjacent to EM groups, with whom we
share equipment and communicate on a daily basis. The Max Planck Institute of
Biochemistry (MPIB) has a strong focus on EM and tomography led by the
Department of Prof Wolfgang Baumeister. In addition to the current EM infrastructure,
our institute is in the process of establishing an EM Core Facility, with a
separate Titan Halo equipped with a direct detector already on site. Outstanding
state-of-the-art infrastructure for biochemistry, biophysics and X-ray
crystallography is housed directly in our department.</span></p><p class="MsoNormal" style="text-align:justify;line-height:150%"><span style="mso-bidi-font-family:Helvetica;color:#1A1A1A">The position is available
immediately, for 3 years, and is funded by the Max Planck Society, an ERC
Advanced grant and the Louis Jeantet Foundation.</span></p><p class="MsoNormal" style="text-align:justify;line-height:150%"><span style="mso-bidi-font-family:Helvetica;color:#1A1A1A">Please contact me (<a href="mailto:conti@biochem.mpg.de">conti@biochem.mpg.de</a>) for further information.</span></p><p class="MsoNormal" style="text-align:justify;line-height:150%"><span style="mso-bidi-font-family:Helvetica;color:#1A1A1A">Best wishes</span></p><p class="MsoNormal" style="text-align:justify;line-height:150%">Elena</p>
<!--EndFragment--></font></p><p class="MsoNormal" style="text-align:justify"><span style="mso-bidi-font-family:
Helvetica;color:#1A1A1A"><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">_______________________________</span></span></span></span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">Elena Conti</span></span></span></span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">Max Planck Institute of Biochemistry</span></span></span></span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">Structural Cell Biology Department</span></span></span></span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><br class="khtml-block-placeholder"></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">Am Klopferspitz 18</span></span></span></span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">D-82152 Martinsried</span></span></span></span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">Germany</span></span></span></span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><br class="khtml-block-placeholder"></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">Tel : +49 (89) 85 78 36 02</span></span></span></span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">Fax: </span></span></span></font><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); ">49 (89) 85 78 36 05</span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><span class="Apple-style-span" style="color: rgb(179, 179, 179); "><a href="mailto:conti@biochem.mpg.de">conti@biochem.mpg.de</a></span></span></span></span></span></span></font></div><div style="font-size: 12px; color: rgb(0, 0, 0); "><font class="Apple-style-span" color="#B3B3B3"><div style="margin-top: 0px; margin-right: 0px; margin-bottom: 0px; margin-left: 0px; "><a href="http://www.biochem.mpg.de/conti">www.biochem.mpg.de/conti</a></div><div><br></div></font></div></span></p><p class="MsoNormal" style="text-align:justify"><span style="mso-bidi-font-family:
Helvetica;color:#1A1A1A"><o:p> </o:p></span></p>
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