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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><b><span style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Postdoc positions available in the Nicastro Lab<o:p></o:p></span></b></p><p class=MsoNormal><b><span style='font-size:12.0pt;font-family:"Times New Roman","serif"'><o:p> </o:p></span></b></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Several postdoctoral positions are available immediately (and later) in the structural cell biology laboratory of Daniela Nicastro (<a href="http://www.bio.brandeis.edu/nicastrolab/">www.bio.brandeis.edu/nicastrolab/</a>; currently at Brandeis University* and as of summer/fall 2015 at the University of Texas Southwestern Medical Center**). Our laboratory uses a wide variety of methods (structural, genetic and biochemical) to study the 3D structure and function of molecular motors, cytoskeletal assemblies, such as cilia and flagella, and other subcellular structures (e.g. host-virus interactions and cancer-relevant complexes). <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman","serif"'><o:p> </o:p></span></p><p class=MsoPlainText><span style='font-family:"Times New Roman","serif";background:white'>Candidates should have a PhD in sciences and </span><span style='font-family:"Times New Roman","serif"'>enjoy working as part of an active research team. Previous experience in structural biology would be an advantage, but is not required. Of particular interest would be previous knowledge in one of the following techniques/topics: cryo-EM/ET, X-ray crystallography, focused-ion-beam (FIB) milling, cancer cell biology or ciliate genetics.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman","serif";background:white'><o:p> </o:p></span></p><p class=msonospacing0 style='margin:0in;margin-bottom:.0001pt'>Please <b>apply by email to Dr. Nicastro [nicastro@brandeis.edu]</b> and include a CV, brief statement of research experience and interests, and contact information for three references.<o:p></o:p></p><p class=msonospacing0 style='margin:0in;margin-bottom:.0001pt'><o:p> </o:p></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman","serif"'>*) <b>Brandeis</b> <b>University</b> (eight miles west of Boston) has an EM facility that offers an excellent environment for cryo-EM and image processing: a Tecnai F30 and F20, two smaller TEMs, FEI Falcon II direct electron detector, Gatan post-column energy filter, several Gatan CCD cameras, 3 plunge freezers (incl. CP3 and Vitrobot), a Correlative Light and Electron Microscopy (CLEM) facility with high pressure freezer, automatic freeze-substitution device and cryo-ultramicrotome, a Linkam cryo-light microscope stage, and a computer facility with a Linux cluster.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman","serif"'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:12.0pt;font-family:"Times New Roman","serif"'>**) <b>UTSW</b> (Dallas) will have an even better EM facility with a new FEI Titan Halo with phase-plates, Gatan post-column energy filter and two direct electron detectors (including a post-filter K2), a new FEI Scios cryo-FIB, a JEOL2200FS with K2, and the same accessory instrumentation mentioned above (including CP3 and Vitrobot plunge-freezers, high-pressure freezer, freeze-substitution device, cryo-ultramicrotome, Linkam cryo-LM stage, high-performance computing cluster); in addition, UTSW provides an algae culture room, and a plethora of shared equipment and core facilities, including facilities for x-ray crystallography and mass-spec. <o:p></o:p></span></p><p class=msonospacing0 style='margin:0in;margin-bottom:.0001pt'><o:p> </o:p></p><p class=msonospacing0 style='margin:0in;margin-bottom:.0001pt'>Also next year, UTSW will be advertising for a <b>facility manager for their newly expanded cryo-EM facility</b>; if you are interested, please feel free to contact Dr. Nicastro for further information. <o:p></o:p></p><p class=msonospacing0 style='margin:0in;margin-bottom:.0001pt'><o:p> </o:p></p><p class=msonospacing0>********************************************<br>Dr. DANIELA NICASTRO<br>MS 029, Rosenstiel Center<br>Brandeis University<br>415 South Street<br>Waltham, MA 02454-9110<o:p></o:p></p><p class=msonospacing0>Phone: (781) 736-2408<br>Fax.: (781) 736-2419<br>email: <a href="mailto:nicastro@brandeis.edu">nicastro@brandeis.edu</a><br>http://www.bio.brandeis.edu/nicastrolab/<br>*******************************************<o:p></o:p></p></div></body></html>