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We are pleased to announce the EMBO practical course on image
processing for cryo-electron microscopy in Birkbeck College, London.
This 10 day course will run from 10-20 September <a
class="moz-txt-link-freetext"
href="http://www.ismb.lon.ac.uk/embocourse.html">http://www.ismb.lon.ac.uk/embocourse.html</a>
<br>
<br>
Deadline for applications: <u>Friday 1 June 2007.</u> .
<br>
<br>
The aim of the course is to teach the basic principles and practical
aspects of image processing to bioscientists and structural biologists
wishing to determine macromolecular structures by cryo electron
microscopy (EM). The course will concentrate on processing of single
particle images, and will be aimed at advanced PhD students and
postdocs working on projects producing cryo EM images for structural
analysis. Familiarity with UNIX would be an advantage. Morning sessions
will include three 50-minute lectures, breaks and a discussion period.
A 3-hour practical would take place in the afternoon, with discussion
time at the end. After dinner there will be research seminars or
student presentations.
<br>
<br>
The course will cover:
<br>
<br>
* Basic concepts of Fourier analysis
<br>
* Principles of TEM image formation and contrast transfer
<br>
* Image acquisition and pre-processing
<br>
* Symmetry and alignment
<br>
* Multivariate statistical analysis and eigenimages
<br>
* Determination of orientations for 3D reconstruction
<br>
* Angular reconstitution
<br>
* Contrast transfer function correction
<br>
* Methods of 3D reconstruction
<br>
* Icosahedral reconstruction
<br>
* Interpretation: Atomic structure fitting into EM maps
<br>
<br>
<br>
<br>
The following people will be speaking at the course: Nicolas Boisset,
Bridget Carragher, Stephen Fuller, Felix de Haas, Marin van Heel,
Richard Henderson, Kay Grunewald<b><span class="style82"><strong></strong></span></b>,
Carolyne Moores, Elena Orlova, Laurence Pearl, Neil Ranson, Helen
Saibil, David Stuart, Maya Topf, Nigel Unwin<br>
<br>
Applications are invited from PhD students and researchers in EM. There
is no course fee except for industrial attendees in which case a fee is
payable directly to EMBO. Food and accommodation will be provided
throughout the course but all attendees must pay for and arrange their
own travel.
<br>
<br>
Applications should include: a Curriculum vitae; a publication list; a
short description of your current work and future plans; an explanation
of why attendance at the course would further the applicant's own
research.<br>
<br>
Applications should be sent by mail to:<br>
Anne-Cécile Maffat <br>
Institute of Structural Molecular Biology<br>
School of Crystallography<br>
Birkbeck<br>
Malet Street<br>
London WC1E 7HX<br>
United Kingdom
<p class="style65"><em>Or by email to:</em><br>
<a href="mailto:a.maffat@mail.cryst.bbk.ac.uk">a.maffat@mail.cryst.bbk.ac.uk</a>
</p>
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~<br>
<pre class="moz-signature" cols="72">Dr. Elena Orlova
Dept. of Crystallography Tel: (+44) (0)20 7631 6845
Birkbeck College Fax: (+44) (0)20 7631 6803
University of London
Malet Street
London WC1E
UK
e-mail: <a class="moz-txt-link-abbreviated" href="mailto:e.orlova@mail.cryst.bbk.ac.uk">e.orlova@mail.cryst.bbk.ac.uk</a>
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