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<p class="style65"><span style="font-family: Arial;">We are pleased to
announce the
<em>EMBO practical course on image processing for cryo-electron
microscopy</em>.
This 10 day course will run from <em><b>4-14 September <a
href="http://www.ismb.lon.ac.uk/embocourse.html"><span
style="font-style: normal;">http://www.ismb.lon.ac.uk/embocourse.html</span></a><o:p></o:p></b></em></span></p>
<p class="style65"><em><b><span style="font-family: Arial;"><span
style=""> </span></span></b></em><u>Deadline for applications:
<b>Wednesday 1 June 2005</b>.</u> </p>
<p class="style65"><span style="font-family: Arial;">The aim of the
course is to
teach the basic principles and practical aspects of image processing to
bioscientists and structural biologists wishing to determine
macromolecular
structures by cryo electron microscopy (EM). The course will
concentrate on
processing of single particle images, and will be aimed at advanced PhD
students and postdocs working on projects producing cryo EM images for
structural analysis. Familiarity with UNIX would be an advantage.
Morning
sessions will include three 50-minute lectures, breaks and a discussion
period.
A 3-hour practical would take place in the afternoon, with discussion
time at
the end. After dinner there will be research seminars or student
presentations.
<o:p></o:p></span></p>
<p class="style65"><span style="font-family: Arial;">The course will
cover:<o:p></o:p></span></p>
<ul type="disc">
<li class="MsoNormal" style=""><span style="font-family: Arial;">Basic
concepts of Fourier analysis<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Principles
of TEM image formation and contrast transfer<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Image
acquisition and pre-processing<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Symmetry
and alignment<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Multivariate
statistical analysis and eigenimages<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Determination
of orientations for 3D reconstruction<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Angular
reconstitution<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Contrast
transfer function correction<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Methods
of 3D reconstruction<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Icosahedral
reconstruction<o:p></o:p></span></li>
<li class="MsoNormal" style=""><span style="font-family: Arial;">Interpretation:
Atomic structure fitting into EM maps</span></li>
</ul>
<p class="style65"><span style="font-family: Arial;"><!--[if !supportEmptyParas]--> <!--[endif]--><o:p></o:p></span></p>
<p class="style65"><span style="font-family: Arial;">The following
people will be
speaking at the course:<strong> Nicolas Boisset, Bridget Carragher,
Tony
Crowther, Stephen Fuller, Felix de Haas, Marin van Heel, Richard
Henderson,
Bram Koster, Elena Orlova,</strong><span class="style79"> <b>Neil
Ranson, Helen
Saibil, David Stuart, Niels Volkmann</b></span><b><o:p></o:p></b></span></p>
<p class="style65"><em><span style="font-family: Arial;"><!--[if !supportEmptyParas]--> <!--[endif]--><o:p></o:p></span></em></p>
<p class="style65"><span style="font-family: Arial;">Applications are
invited from
PhD students and researchers in EM. There is no course fee except for
industrial attendees in which case a fee is payable directly to EMBO.
Food and
accommodation will be provided throughout the course but all attendees
must pay
for and arrange their own travel.<o:p></o:p></span></p>
<p class="style65style31"><em><span style="font-family: Arial;">Applications
should
include:</span></em><span style="font-family: Arial;"> a <em>Curriculum
vitae;</em>
a publication list; a short description of your current work and future
plans;
an explanation of why attendance at the course would further the
applicant's
own research.<o:p></o:p></span></p>
<p class="style65"><em><span style="font-family: Arial;">Applications
should be
sent by mail to:</span></em><span style="font-family: Arial;"><br>
Tim Hoe<br>
Institute of Structural Molecular Biology<br>
School of Crystallography<br>
Birkbeck<br>
Malet Street<br>
London WC1E 7HX<br>
United Kingdom<o:p></o:p></span></p>
<em><span style="font-size: 12pt; font-family: "Times New Roman";">Or
by email to: </span></em><span
style="font-size: 12pt; font-family: "Times New Roman";"><a
href="mailto:t.hoe@mail.cryst.bbk.ac.uk">t.hoe@mail.cryst.bbk.ac.uk</a></span>
<pre class="moz-signature" cols="72">--
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Dr. Elena Orlova
Dept. of Crystallography Tel: (+44) (0)20 7631 6845
Birkbeck College Fax: (+44) (0)20 7631 6803
University of London
Malet Street e-mail: <a class="moz-txt-link-abbreviated" href="mailto:e.orlova@mail.cryst.bbk.ac.uk">e.orlova@mail.cryst.bbk.ac.uk</a>
London WC1E 7HX
</pre>
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