[3dem] Postdoc position at UTSW Medical Center, O'Donnell Brain Institute

[Sarah]

Dear All,
I am excited to announce a Postdoc opening in my newly formed group at UT
Southwestern Medical Center (UTSW). Ad is below.

Please spread the word, and kindly forward to potential candidates. Thank
you!
Stay well, best regards,
Sarah


The Shahmoradian lab at the UT Southwestern (UTSW) Medical Center O’Donnell
Brain Institute, Center for Alzheimer’s and Neurodegenerative Diseases in
Dallas, Texas, is seeking a full-time Postdoctoral Scientist to apply
cellular structural biology techniques and complementary methods to
investigate the macromolecular basis of protein aggregation and membrane
remodelling in neurons and mammalian tissues.


Main methods are cryo-focused ion beam specimen preparations, cryo-electron
tomography and 3D processing/sub-tomogram averaging, together with
correlative light/electron microscopy.

*Requirements:*

   - Ph.D. in life science or engineering (or due to complete within 6
   months)
   - Demonstrated ability to have worked independently and in a team
   - Track record with original contributions
   - Prior experience with cryo-electron microscopy/tomography and
   computational processing techniques
   - Machine learning experience is a plus


*Working environment:*
Successful candidates will benefit from excellent infrastructure and
growing resources available here at UTSW:

   - Newly purchased Thermo Fisher Aquilos II cryoFIB/SEM equipped with
   both internal cryo-widefield and external Leica cryo-confocal fluorescence
   microscopes
   - 2 Titan Krios cryo-electron microscopes with direct electron
   detectors, including one with the latest generation cold field emission gun
   and Selectris-X energy filter (other has Volta phase plate and BioQuantum
   energy filter)
   - Talos Arctica cryo-electron microscope with K3 direct electron
   detector and Volta phase plate
   - Talos Glacios cryo-electron microscope with Falcon direct electron
   detector and Ceta-D camera
   - Custom-engineered, super-resolution, light-sheet and cleared tissue
   microscopes
   - UTSW Whole Brain Microscopy Facility with several high-throughput
   microscopes including two state-of-the-art multi-photon microscopes with
   integrated precision vibratomes
   - UTSW Green Center for Systems Biology with ~25 isolated microscope
   development bays equipped with optical tables
   - UTSW Department of Bioinformatics with BioHPC, a high-performance
   computing and storage facility equipped with ~1000 CPU and ~120 GPU nodes
   connected to 50 PB of storage for in-house data analysis (All instruments
   have direct mounts to this computing infrastructure)


*University highlights:*

   - Highly collaborative and inclusive environment encompassing the entire
   spectrum of basic, translational, and clinical research
   - Six Nobel Prize Winners and 25 members of the National Academy of
   Sciences
   - Ranked No. 1 in the world among healthcare institutions in biomedical
   sciences (Nature Index 2019)
   - Several employee benefits including free health insurance for
   full-time staff, and excellent coverage for dependents.


*Living environment:*

The Dallas-Fort Worth Metroplex is home to:

   - Top educational school systems in Texas and the nation
   - Dallas Arts District, the largest contiguous urban arts district in
   the United States, covering contiguous ~120 acres (0.5 square kilometer)
   - “Deep Ellum”, the live music capital of North Texas and a hub for the
   performing arts from theater to comedy
   - Several parks and lakes great for boating and camping
   - Multitude of great dining and shopping options
   - Central location in the US, with easy access to major international
   airport and a smaller national airport


To apply, please email sarah.shahmoradian at utsouthwestern.edu with your
cover letter and CV.





---

Sarah Shahmoradian, PhD

Assistant Professor

Center for Alzheimer’s and Neurodegenerative Diseases

Department of Biophysics

Peter O’Donnell Jr. Brain Institute


*UT** Southwestern*

Medical Center

The future of medicine, today.
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