[3dem] Postdoc positions in Yuan He's group at Northwestern University

[Yuan He]

Dear community,

The He lab in the Department of Molecular Biosciences at Northwestern seeks a highly motivated and talented postdoctoral fellow to work at the interfaces of cryo-EM and gene regulation or DNA repair. Research in the lab is focused on understanding the molecular mechanisms by which large, multi-subunit complexes engage in DNA-centric processes using cryo-EM and other biophysical, biochemical and genomic approaches. We focus on two main topics: (1) how eukaryotic gene transcription is regulated at different stages, and (2) how various types of DNA damage are repaired and why deficiencies in these repair pathways lead to pathology of cancer predisposition or accelerated aging. For more information, please see our website: https://urldefense.com/v3/__https://sites.northwestern.edu/cryoem/__;!!Mih3wA!QpSoxTKIB-qxc-eOkLu2S51u8G25MsC2n6Rt6dXfIu6JwjFtBH1nARF8N64XQsoNMw$ .

Candidates who have recently finished or will soon complete their PhD degree with a strong research track record are encouraged to apply. Candidates with expertise in one or more areas of biochemistry, biophysics or genomics are highly desired. While prior experience with cryo-EM, mammalian cell culture, or genome editing would be highly advantageous, we welcome researchers from all backgrounds. To apply, please send a cover letter, your CV, and the contact information of three references to yuanhe at northwestern.edu<mailto:yuanhe at northwestern.edu>.

Recent Publications:

Chen, S., Lee, L., Naila, T., Fishbain, S., Wang, A., Tomkinson, A.E., Lees-Miller, S.P. and He, Y. (2021) Structural basis of Long-range to Short-range synaptic transition in NHEJ. Nature, doi: 10.1038/s41586-021-03458-7

Abdella, R., Talyzina, A., Inouye, C., Tjian, R. and He, Y. (2021) Structure of the human Mediator-bound transcription preinitiation complex. Science, 372:52-56

Han, Y., Reyes, A.A., Malik, S. and He, Y. (2020) Cryo-EM structure of SWI/SNF complex bound to a nucleosome. Nature, 579, 452-5.

Yuan He, Ph.D
Assistant Professor
Department of Molecular Biosciences
Northwestern University
2205 Tech Drive, Hogan 2-100
Evanston, IL 60208-3500


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