[3dem] Postdoc positions in virus infection, Plevka group, CEITEC, Czech Republic

Pavel Plevka pavel.plevka at ceitec.muni.cz
Tue Oct 22 01:33:44 PDT 2019


Dear all,

I am looking to recruit two post-doctoral researchers experienced in cryo-EM, cryo-ET, or X-ray crystallography. The projects are focused on characterising the replication of viruses in situ:

We study the infection of enteroviruses by a combination of FIBM and cryo-ET to determine the mechanism of enterovirus genome delivery into a host cell and changes in intra-cellular organisation induced by infection. We complement the whole-cell studies by high-resolution cryo-EM of virus genome release under biologically relevant conditions in vitro.

We employ cryo-ET and light microscopy to characterise the mechanisms that tailed phages, potential phage therapy agents, employ to invade a biofilm and infect bacteria. We use the cryo-ET to determine the functions of bacterial factors in phage genome delivery and characterise phage assembly. We employ time-lapse fluorescence microscopy to establish the relationship between the stage of biofilm development and its susceptibility to phage infection.

Details about my research group can be found here:

http://plevkalab.ceitec.cz <http://plevkalab.ceitec.cz/>
Our in house cryo-EM facility:

https://www.ceitec.eu/cryo-electron-microscopy-and-tomography-core-facility/cf94 <https://www.ceitec.eu/cryo-electron-microscopy-and-tomography-core-facility/cf94>
Please get in touch with me if you have any questions.

Pavel





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Pavel Plevka
Laboratory of Structural Virology
CEITEC, Masaryk University
Kamenice 5 / A35
Brno, 625 00, Czech Republic
Phone: +420 549 49 7756
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