[3dem] Job Opportunity for Cryo-EM Specialist at Genentech Inc., California, USA

[Claudio Ciferri]

Dear All,
just a quick reminder to encourage any remaining applications for the Job
Opportunity for Cryo-EM Specialist at Genentech Inc., California, USA.

We aim to collect CVs until the end of this week and continue with the
interview process shortly after.

Please feel free to contact me, would you require any additional
information.
Looking forward to receiving your application.
Best

Claudio






















*The Department of Structural Biology at Genentech is expanding its cryo-EM
effort to support research and drug discovery and has an exciting
opportunity for a very motivated individual to join our cryo-EM team as a
System Specialist II or Senior System Specialist.You can apply to this
position using this link.The successful candidate will be a technical
expert in at least one of the following areas:Sample preparation and
optimization for cryo-EM: the candidate should have a strong background and
proven track record in protein biochemistry, cryo-EM grid preparation and
sample optimization for cryo-EM structure determination. Hands-on
experience with different protein classes (i.e. soluble, membrane and/or
secreted) is highly desirable. Experience with one of the automatic
vitrification systems (Chameleon, Vitrojet, Cryo-writer, etc.) would be
considered a plus. Excellent communication, interpersonal and
organizational skills are essential. Data collection and cryo-EM
operations: the candidate should have in-depth technical knowledge of
electron microscopes, and proven proficiency in cryo-EM grid preparation
and manual and automated data collection on 200keV and 300keV systems using
SerialEM or EPU. Experience with on-the-fly single-particle data
processing, the collection and/or processing of microED data will be
considered a plus. The successful candidate will have excellent
communication, interpersonal and organizational skills, as well as a proven
track record of support and coordination of multiple projects and users in
a cryo-EM facility set-up.The successful candidate will be part of a
diverse and stimulating research environment focused on enabling research
and drug discovery to help patients in need. While embedded within the
Genentech pipeline, the selected candidate would also have the opportunity
to initiate independent or collaborative research efforts.  The cryo-EM
 facility at Genentech houses a Titan Krios equipped with post-GIF K2, a
Talos 200C equipped with CetaD, a Glacios equipped with K2 (to be delivered
August 2019) and another Titan Krios equipped with energy filter and K3 (to
be delivered January 2020), as well as the usual ancillary equipment for
sample preparation and plunge-freezing.Required qualifications: Ph.D. or
equivalent in biochemistry, biophysics, protein engineering, and/or
structural biology, with hands-on experience in cryo-EM sample preparation
and optimization and/or data collection and equipment maintenance is
required. Productive postdoctoral training and/or industry experience
highly desirable.Additional desired qualifications:- Hands-on experience
optimizing the production of challenging protein targets for structural
studies- Proficiency in cryo-EM structure determination or modeling using
one or more software packages- Experience with MicroED data collection and
data processing- Experience with protein engineering and/or design
approaches- Analysis, design, and/or computational approaches to
investigate ligand-protein complexes*




-- 
*Claudio Ciferri*
Sr Scientist - Structural Biology
Genentech, Inc.
1 DNA Way, MS: 247
South San Francisco, CA 94080

office: (650) 4674946
cell: (510) 5013763
ciferri.claudio at gene.com
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