[3dem] Microscopy & Microanalysis meeting (M&M 2019): August 4-8, 2019 Portland OR

[Melanie Ohi]

Dear Colleagues,

 We would like to bring to your attention to the many 3DEM-related plenary talks, symposia and educational opportunities at the upcoming Microscopy & Microanalysis meeting (M&M 2019). M&M 2019 will be held August 4-8, 2019 in Portland, OR.


 The Plenary Speakers will be two of the three 2017 Laureates of the Nobel Prize in Chemistry: Joachim Frank and Richard Henderson. 

There are three cryo-EM focused symposium: 3D Structures: from Macromolecular Assemblies to Whole Cells (B07), Cryo-EM - from Physics to Cell Biology: Honoring the Remarkable Legacy of Ken Downing (B08), and Advances in Cryo-EM Technology (A12), as well as a number of tutorials and workshops focused on cryo-EM techniques.


 The full Online M&M 2019 Program information can be found at: https://www.microscopy.org/MandM/2019/ <https://www.microscopy.org/MandM/2019/>
 The deadline for paper submission is February 15th 2019. This is going to be a great meeting in a fun city. Do not forget that students and post-doctoral fellows benefit from reduced rates. We hope to see you in Portland!


 All the best,


M&M 2019 Program Committee

 

 SYMPOSIA:


 B07: 3D Structures: from Macromolecular Assemblies to Whole Cells (3DEM FIG)


ORGANIZERS: Melanie Ohi, Elitza Tocheva and Teresa Ruiz.

Our understanding of the 3D structure and functional subtleties of complex biological systems has skyrocketed due to recent advances in EM imaging technology and hybrid methodologies. This symposium will highlight structural studies of macromolecules, microorganisms, cells, and tissues using state-of-the-art high-resolution techniques. These techniques include electron crystallography, single particle cryo-EM, helical reconstruction, STEM; AFM, X-ray crystallography, and molecular modeling. Biological topics of interest include: cellular architecture, metabolism, trafficking, communication, and division; gene regulation, transcription, and translation; host-pathogen interactions and virus structure; In situ studies using TEM and SEM, and all aspects of structure-function studies of biological assemblies.

 

B08 - Cryo-EM - from Physics to Cell Biology: Honoring the Remarkable Legacy of Ken Downing

ORGANIZERS: Melanie Ohi and Eva Nogales.

This symposium will honor Dr. Ken Downing's legacy by showcasing work in single particle cryo-EM, cryo-electron tomography, and microscopy methods that build on his seminal discoveries. Dr. Downing, MSA Fellow and former president, was a titan in the field of electron microscopy (EM). His scientific accomplishments span an amazing range of widely-recognized techniques and methods. Work in his laboratory led to the first high-resolution structure of tubulin using electron crystallography and he made important contributions in the current "resolution revolution" in single particle cryo-EM. Perhaps even more importantly, Ken Downing was a wonderful mentor to the next generation of scientists.

 

A12 - Advances in Cryo-EM Technology

ORGANIZERS: Mike Marko, Anchi Cheng and Radostin Danev.

Cryo-EM provides single-particle maps with resolution in the sub-3Â range, and sub-tomogram-averaged maps in the 1 nm range, all with the sample in a near-native, hydrated state. This symposium will highlight new technology for specimen preparation, new instrumentation and software that improves the image quality, and processing advancement that pushes the resolution boundary. The symposium will have invited speakers who are key to the latest developments, and will include contributed papers from participants in this exciting field.

 

The meeting showcases the latest technical and scientific developments in the field of microscopy and microanalysis. Of great interest are the following stimulating tutorials, Sunday short courses:

 TUTORIALS:


 X43 Expanding the Computational Toolbox for CryoEM


PRESENTER: Alberto Bartesaghi.

X44 Electron Optics for CryoEM: Facts and Myths

PRESENTER: Wim Hagen.

X45 Tips and Tricks for High-Pressure Freezing / Freeze Substitution

PRESENTER: Martin Schauflinger.

 

SHORT SUNDAY COURSES:

 X-10 High-Resolution Structure Determination by Cryo-EM: What Could Possibly Go Wrong?


LEAD INSTRUCTORS: Anchi Cheng and Steve Ludtke.

 For students and Post-docs there is a pre-meeting congress on Saturday August 3rd, 2019:


X60 Third Annual Pre-Meeting Congress for Students, Post-Docs, and Early-Career Professionals. 

 

The full Online M&M 2019 Program information can be found at: https://www.microscopy.org/MandM/2019/ <https://www.microscopy.org/MandM/2019/>
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Melanie Ohi, Ph.D.
Rowena G. Matthews Collegiate Professor in the Life Sciences
Research Associate Professor
University of Michigan Life Sciences Institute
Associate Professor Dept. of Cell and Developmental Biology
University of Michigan
210 Washtenaw Avenue, 6th floor, Room 6401
Ann Arbor, MI 48109-2216

Office Phone: (734) 763-6493
E-mail: mohi at umich.edu

Lab Phone: (734) 763-6147

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