[3dem] model-map FSC @ 0.25 cutoff? (YOU ASKED FOR IT!)

[Marin van Heel]

Hi Gabe,

After our #resolutionretribution paper nobody wants to talk about FSC 
values any more...  Unfortunately, due to early errors in the underlying 
statistics
virtually all resolution criteria in cryo-EM are flawed (including: 
FSC.143; FSC.5, SSNR, Gold-Standard FSC; etc).
In spite of having pissed off all our peers, we still hope the paper 
will reach print soon. ;)

Cheers
Marin

https://www.biorxiv.org/content/early/2017/11/24/224402

YES: you asked for it!  But the damages have already been done over 
decades....

===================

On 03/05/2018 20:30, Gabriel Lander wrote:
> Hi all,
> I've recently been seeing model-to-map FSCs being reported using a cutoff of 0.25 - I must have missed this discussion or the paper describing the rationale for this cutoff value instead of 0.5. Can someone fill me in?
> -gabe
>
> PS. I take full responsibility for all repercussions/damages stemming from asking an FSC-based question on this listserv.
> _______________________________________________
> 3dem mailing list
> 3dem at ncmir.ucsd.edu
> https://mail.ncmir.ucsd.edu/mailman/listinfo/3dem


-- 
==============================================================

     Prof Dr Ir Marin van Heel

     Laboratório Nacional de Nanotecnologia - LNNano
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     Leiden University
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