[3dem] cryoEM of ribosomal complexes - postdoctoral position (up to 5 years): UCL and Birkbeck College

[Christodoulou, John]

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Postdoctoral researcher: cryo electron microscopy of co-translational protein folding


We are seeking to appoint a Research Associate to apply cryo-electron microscopy to study the molecular basis of co-translational protein folding as it occurs within living systems. This emerging project will be complemented by established research within the laboratory which applies biomolecular NMR spectroscopy to to examine the structure, dynamics and folding of a nascent chain as it is being synthesised on the ribosome.




The work will be undertaken at the Institute of Structural and Molecular Biology at UCL and Birkbeck College, as part of the Institute of Structural and Molecular Biology (http://www.ismb.lon.ac.uk/), and via our satellite laboratory at the Francis Crick Institute.  The ISMB is equipped with state-of-the-art facilities, including state-of-the-art cryo-electron microscopy facilities at the Birkbeck Electron Microscopy and Image Processing Laboratory and the work will be undertaken via close collaborative links with Prof Elena Orlova.



This Wellcome Trust funded post is funded for one year in the first instance with the possibility for extension (up to 5 years). The starting salary will be Grade 7, spine point 29: £34,056.



Key Requirements

Applicants should have a relevant PhD in cryo-electron microscopy and/or tomography, and with experience in molecular dynamics simulations and/or recombinant protein purification. Experience in studying ribosomes, protein (mis)folding and/or protein-based interactions would be highly advantageous.


The candidate joining the laboratory will be a highly motivated individual that can work both independently as well as a part of a team, and have a willingness and desire to develop their work through the supervision of PhD students in collaboration with other group members and collaborators.

Further Details



Further Details and an application form can be found at: http://www.ucl.ac.uk/biosciences/vacancies



For any queries regarding the application process, please contact Biosciences Staffing on biosciences.staffing at ucl.ac.uk<mailto:biosciences.staffing at ucl.ac.uk> and quote the reference number 1664437.



 For informal enquiries about the post, please contact: Prof. John Christodoulou (j.christodoulou at ucl.ac.uk<mailto:j.christodoulou at ucl.ac.uk>)

Closing Date: 27 Sep 2017
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