[3dem] PDRA Opportunity in Leeds

Glyn Hemsworth G.R.Hemsworth at leeds.ac.uk
Fri Mar 3 07:35:02 PST 2017

Dear All,

Could I please bring the below PDRA opportunity available at the University of Leeds to the attention of the EM community. Please note the deadline for applications is 21st March 2017.

The full candidate brief can be downloaded from the following web address:


To apply for the position please register for an account on the Leeds website and submit a covering letter, together with a CV including details of at least two references.

Funded by the BBSRC the position is available for an initial 2 year period, with the possibility of extending to 4 years. The position will suit someone interested in redox proteins, structural biology and biotechnology. Please feel free to get in touch with informal enquiries about the role. Thanks and best wishes,


Glyn Hemsworth
Astbury Building, Room 10.107
Faculty of Biological Sciences,
University of Leeds, Leeds, LS2 9JT, UK
Tel: (+44) 0113 3434 349
Email: g.r.hemsworth at leeds.ac.uk<mailto:g.r.hemsworth at leeds.ac.uk>

Research Fellow

Are you an ambitious researcher looking for your next challenge? Do you have an established background in Structural Biology, Biochemistry or Chemistry? Do you want to further your career in one of the UKs leading research intensive Universities?

You will investigate the structure and function of a range of proteins, and their complexes, as potential activators of a class of enzymes known as lytic polysaccharide monooxygenases (LPMOs), (find out more in this recent review<http://www.cell.com/trends/biotechnology/abstract/S0167-7799(15)00192-4?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0167779915001924%3Fshowall%3Dtrue>). LPMOs have emerged as key enzymes in biomass conversion, both in nature and in the applied setting of a biorefinery. Using a combination of structural, biophysical, and biochemical methods we are seeking to characterise the molecular mechanisms used in nature to shuttle electrons to LPMOs. The knowledge gained from this research is of considerable interest from both a fundamental and applied standpoint and will ultimately be used in protein engineering approaches to produce more efficient enzyme systems to be used in the biorefinery.

Funded by the BBSRC, you will be based in the newly established laboratory of Dr Glyn Hemsworth in the Faculty of Biological Sciences and the Astbury Centre for Structural Molecular Biology. With the recent £17 million investment in the Astbury Biostructure lab to complement the already superb infrastructure for structural molecular biology, Leeds represents the perfect environment for you to learn new techniques whilst contributing vital knowledge towards realising the development of lignocellulosing biofuels as a more sustainable energy source for the future.

You should have, or be close to completing a PhD in Structural Biology, Biochemistry, Chemistry or a related discipline, where practical experience of cryo-electron microscopy or X-ray crystallography is essential. You will be expected to show enthusiasm for engaging in inter-disciplinary research and expanding your knowledge and expertise into new areas. Experience of studying protein-protein interactions would also be an advantage.

To explore the post further or for any queries you may have, please contact:

Glyn Hemsworth

Tel: 0113 343 4349, email: g.r.hemsworth at leeds.ac.uk<mailto:g.r.hemsworth at leeds.ac.uk>

Location:       Leeds - Main Campus
Faculty/Service:        Faculty of Biological Sciences
School/Institute:       School of Molecular & Cellular Biology
Category:       Research
Grade:  Grade 7
Salary:         £32,004 to £38,183 p.a.
Contract Type:  Fixed Term (Fixed term for 2 years due to funding - optional 4 years)
Closing Date:   Tuesday 21 March 2017
Reference:      FBSMB1100

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