[3dem] 2 Postdoctoral Positions in cryo3D macromolecular imaging

David A. Agard agard at msg.ucsf.edu
Thu Oct 10 05:31:03 PDT 2013

2 Postdoctoral Positions in cryo3D macromolecular imaging

Two postdoctoral positions are available immediately in the HHMI laboratory of David Agard at UCSF. Our laboratory uses a wide variety of structural methods to understand fundamental molecular mechanisms in protein folding and cytoskeletal organization. 

One project focuses on high resolution single particle cryoEM studies of Hsp90 molecular chaperone complexes, and the other will utilize cryoEM tomography and sub-volume averaging to examine the newly discovered phage tubulin cytoskeleton within bacterial cells.

UCSF is a spectacular environment for cryoEM. We have a Polara, an F20 with 8k Tietz camera, a T20 and a T12, 2 Vitrobots, etc. Our Polara is equipped with 2 K2 electron counting cameras, one pre GIF and one post GIF. The GIF is being upgraded to a next generation BioQuantum having significantly advanced performance. These, together with our optimized software for collecting and registering dose fractionated single particle and tomographic images to correct for beam induced motion, provide unprecedented image resolution for both single particle studies and tomography.
The successful candidate should have a PhD but no more than 2-3 years postdoctoral training in structural biology or biophysics and previous experience in electron cryo-microscopy.

Candidates should contact Dr. Agard and include a CV, statement of research interests, and contact information for three references.

David A. Agard, Ph.D.
Howard Hughes Medical Institute and the
Department of Biochemistry and Biophysics
University of California at San Francisco
UCSF  MC 2240
600 16th Street,   room S412D
San Francisco, CA     94158-2517
(415) 476-2521  Phone    E-mail:    agard at msg.ucsf.edu
(415) 476-1902  FAX    Web:    http://www.msg.ucsf.edu/agard

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