[3dem] Postdoctoral Fellow in Structural Virology

[Wei Zhang]

Postdoctoral Fellow in Structural Virology
Institute for Molecular Virology
University of Minnesota-Twin Cities
Minneapolis, MN 55455
Web: www.virology.umn.edu

Description
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A Postdoctoral Fellow is being sought for a collaboration involving the 
application of cryo-electron tomography (cryo-ET) of human T-cell 
leukemia virus particles.  This is a collaborative research project 
between the laboratories of Profs. Wei Zhang, Joachim Mueller and Louis 
Mansky.  Scientists recruited will join a strongly interactive, 
collaborative and collegial research environment. Minneapolis is a 
dynamic and progressive city with outstanding cultural attractions and a 
high standard of living.

Skills
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Candidates are expected to have a strong background in (cryo-)electron 
microscopy /tomography/image processing and analysis or other structural 
biology techniques such as X-ray crystallography or NMR spectroscopy.  
Experience in molecular and cell biology/biochemistry/molecular virology 
is a plus.

Resources
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The cryo-ET data collection will be performed using the TF30 Tecnai FEG 
TEM, which is housed in the Characterization Facility 
(http://www.charfac.umn.edu).  The microscope includes a Gatan image 
filter for electron energy loss spectroscopy and energy filtered 
imaging, as well as high angle annular dark field detector for 
Z-contrast imaging.  Xplore3D, SerialEM, UCSF tomo and Amira software 
are available for TEM/STEM Tomography.  The facility is also equipped 
with a FEI vitrobot, Tecnai Bio-Twin Spirit TEM, FEI iCorr, 
high-pressure freezing/freeze-substitution instruments, cryo-microtome 
and FEG-SEMs.  The facility offers excellent training opportunities for 
electron microscopy related techniques.  The University of Minnesota's 
Supercomputing Institute (http://www.msi.umn.edu) offers an excellent 
computation environment.

Contacts
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Inquiries and applications should be sent to: zhangwei at umn.edu or 
mansky at umn.edu