[3dem] Postdoctoral positions, Emory University, Atlanta GA

[Wright, Elizabeth R.]

POSTDOCTORAL FELLOW POSITIONS, EMORY UNIVERSITY

Postdoctoral fellow positions are available in the Wright laboratory at Emory Universitystarting fall/winter 2012 (http://electronmicroscopy.emory.edu). Research in the lab is focused on bacterial and viral structural biology, with emphasis on 3-D structure/function relationships between host cells and viruses. Areas of interest include cryo-electron tomography of bacteria, bacteria – bacteriophage interactions, paramyxoviruses, and HIV-1. Technology development interests are in the areas of correlative microscopy and phase plate cryo-microscopy.

The first postdoctoral position is aimed at studies of the structure of flagella and type IV pili from several bacterial species. The long-term goal of the project is to understand 1) the structural implications of the incorporation of multiple flagellins into the flagellar filament and 2) the structural variation between T4bP and Flp-type pili at the macromolecular level.

The second postdoctoral position is to develop of correlative microscopy (fluorescent to cryo-EM) techniques and novel macromolecule-specific probes to study aspects of viral fusion, entry, assembly, and trafficking. The viral systems to be studied include HIV-1 and several members of the paramyxovirus family.

Candidates should have an interest in structural biology, bacteriology or virology, and should enjoy working as part of an active research team. Background experience in one (or more) of the following fields is desirable, but not required: bacteriology, virology, (cryo-) electron microscopy, and/or image processing/analysis techniques.

The wet laboratory is within the Division of Pediatric Infectious Diseases and is fully equipped for all aspects of microbiology, molecular biology, molecular virology, and protein biochemistry. The Wright lab has complete access to aJEOL 2200FS 200 kV FEG TEM with an in-column energy filter, Zernike-style phase plates, and high-resolution 4kx4k CCD camera; a JEOL 1400 120 kV TEM with 2kx2k camera; an FEI Vitrobot and a manual grid plunge freezer; a Bal-Tec high pressure freezer and Leica freeze substitution system; and a Leica cryo-ultramicrotome. Emory is a vibrant, multidisciplinary campus withstrong ties to Georgia Tech and other universities within Georgia. Access to facilities in NMR, Mass Spectrometry, and X-ray crystallography are available.

Applicants should include a cover letter describing research experience and interests,curriculum vitae, and names and contact information for three references.

Dr. Elizabeth R. Wright
Emory University
Department of Pediatrics
2015 Uppergate Drive, NE Room: 548
Atlanta, GA 30322
erwrigh at emory.edu<../../../../../Manuscripts/erwrigh at emory.edu>
Website: http://electronmicroscopy.emory.edu

Applications will be reviewed as they are received and until the position is filled.

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