[3dem] Postdoctoral position : cryo EM Grenoble France

[Guy SCHOEHN]

Dear all,


Post doctoral position in Grenoble, France on cryo-EM analysis and 
image reconstruction of the influenza virus polymerase in the groups of 
Guy Schoehn and Rob Ruigrok.


The groups of Guy Schoehn (IBS/UVHCI) Stephen Cusack (EMBL Grenoble) 
and Rob Ruigrok (UVHCI) have been working together for a long time on 
the electron microscopy and biochemistry of isolated influenza virus 
polymerase (NAR 35, 3774-3783 (2007); Nature 458, 914-918 (2009)). The 
Ruigrok group has now produced enough amount of recombinant polymerase 
to do biochemistry and structural biology. The candidate will work 
closely with the biochemists to test samples containing various RNA 
substrates in order to determine the best sample for electron 
microscopy. On this sample cryo-EM and image analysis should lead to the 
first high resolution structure of the influenza polymerase. The Schoehn 
lab is equipped with a 120 KV, 200 KV Lab6 and a 300 KV Polara electron 
microscope. The Ruigrok lab is well equipped for the protein production, 
biochemistry and structural biology. Both labs are part of the Grenoble 
Partnership for Structural Biology. The position is initially for two 
years and funding comes from the Grenoble GRAL Labex. Information: 
guy.schoehn at ibs.fr and ruigrok at embl.fr. Grenoble is in the South of 
France at the foot of the Alps. If you are an electron microscopist, if 
you like beautiful nature and mountain sports, if you like the French 
style of life with good food, this position if for you!

Best

Guy