[3dem] Instructor change, Short course X14 at M&M meeting 2011

Michael Radermacher mraderma at uvm.edu
Wed Aug 3 15:05:25 PDT 2011


Dear All,

As an update to the earlier message, there has been a change in  
instructors for
the Sunday short course X14: 3D Electron Microscopy of Macromolecular  
Assemblies.
The section on docking of X-ray structures will now be taught by Dr.  
Edward Morris from the Structural Biology group at the Institute of  
Cancer Research in London, UK.

Course description (on-site registration is possible):

X14: 3D Electron Microscopy of Macromolecular Assemblies
Teresa Ruiz, Michael Radermacher, and Edward Morris

This short course will provide a comprehensive description of the  
methods used for 3D structure determination of macromolecular  
complexes from electron micrographs. First specimen preparation  
techniques for single particles (deep stain, vitreous ice), will be  
presented and the selection of imaging conditions including low-dose  
imaging. This will be followed by a detailed explanation of image  
processing techniques with special emphasis on the random conical  
reconstruction technique. In the last part structure interpretation  
and docking of X-ray structures to 3D EM densities will be demonstrated.
The techniques described have application in both biological and  
materials science.


-- 
Michael Radermacher, Ph.D., Prof.
University of Vermont
Dept. Molecular Physiology and Biophysics
HSRF 120 / 149 Beaumont Ave
Burlington, VT 05405
USA




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