[3dem] New IMAGIC 4D release

[Marin van Heel]

*IMAGIC-4D release   *

*(www.single-particles.org/methodology)*

*A new version of IMAGIC will be released on the 15th of March 2010.
*

*Whereas IMAGIC programs (since 1980) will automatically loop over 
stacks of 2D images, the new program versions will also automatically 
loop over stacks of 3D volumes present in an IMAGIC input "4D file". *

*All 3D operations are now in-core ensuring fast processing avoiding 
unnecessary input/output operations. The extended IMAGIC 4D file format 
remains compatible with the previous IMAGIC-5 format. All time-critical 
programs exploit MPI parallelization allowing for millions of input 
images to be processed efficiently. *

*Some IMAGIC-4D commands:*

*MSA-RUN: MSA eigenvector data compression (high speed parallelization 
with parallel I/O through local scratch files; terabyte-sized files - 
containing millions of images or 3D volumes - can now be processed. *

*THREED-RECONSTRUCTION (TRUE 3D): Reconstruction of multiple 3D volumes 
using the "exact filter" algorithm and our new 3D-deconvolution 
algorithm. Produces stacks of 3D reconstructions. CPU needs scale 
proportionally with the number of input images. *

*M-R-A (multi-reference alignment): MPI-parallelized alignments and 
Euler angle assignments with respect to references from multiple 3D 
volumes. Various new alignment options (including "brute force"). *

*ANGULAR-RECONSTITUTION: Euler Angle assignments and refinements with 
respect to multiple 3D volumes as anchor sets.*

*"IMAGIC 4D" runs on: Linux/Unix, MAC OS X, and MS Windows XP/7 (32 and 
64 bit).*

================================================================

    Marin van Heel

    Professor of Structural Biology

    Division of Molecular Biosciences
    Faculty of Natural Sciences
    Imperial College London
    Flowers Building (G20)
    South Kensington Campus 
    London SW7 2AZ,        UK
 
    Tel:        + 44 (0)20 7594 5316
    Fax:        + 44 (0)20 7594 5317

    e_mail: m.vanheel(A_T)ic.ac.uk
    and:    <vanheel.office(A_T)ic.ac.uk>
    and:    mvh.office(A_T)gmail.com    
  

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