[3DEM] Reminder: JSB special electron crystallography edition

[B Hankamer]

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Advances in Electron Crystallography of Membrane Proteins:

Call for papers for a special issue of JSB

Ben Hankamer, Henning Stahlberg and Bob Glaeser, Guest 
Editors

Submission Deadline: 1 May
  
The Journal of Structural Biology invites submissions for 
a special issue focusing on recent ‘Advances in Electron 
Crystallography of Membrane Proteins’. 
Electron-crystallography offers many advantages for the 
determination of membrane proteins structures, which is 
one of the great challenges of structural and cell 
biology.
In recent years electron-crystallography of membrane 
proteins has undergone major developments, which enhance 
its natural advantages. These advantages include the fact 
that membrane proteins can be crystallized within a 
near-native lipid bilayer environment, that 2-D crystals 
may sometimes be obtained even though 3-D crystals have 
not been, and that the technique is well suited for the 
crystallization of small and hydrophobic integral membrane 
proteins as well as membrane associated proteins. 
 Functionalized monolayer technology is also opening up 
the possibility of streamlining crystal production and of 
coupling this process to improved protein expression 
techniques. As a resolution of better than 2Å has now been 
reported, it is proven that data can be collected to 
determine not only protein structure but its detailed 
interplay with the components of the lipid bilayer.
This special edition aims to capture the key developments 
that will help to take the electron crystallography field 
to the next phase, from streamlined crystal production and 
structure determination to new levels of resolution. 
Manuscripts in the following areas are specifically (but 
not exclusively) invited:

1.	Membrane protein expression
2.	Membrane protein purification
3.	2D crystallization
4.	Sample preparation for electron microscopy
5.	Automated screening of crystallization trials
6.	Computer image processing and software developments
7.	Recent applications and new structures

Papers can be in the form of research articles or 
mini-reviews that summarize key areas of importance. Prior 
to submission of a minireview, or if you require any 
further information on the suitability of your manuscript 
for inclusion in this special issue, please contact Ben 
Hankamer (b.hankamer at imb.uq.edu.au), Henning Stahlberg 
(HStahlberg at ucdavis.edu), or Bob Glaeser 
(RMGlaeser at lbl.gov) .

The deadline for receipt of manuscripts for the Special 
Issue is 1 May 2006.  Manuscripts will be peer-reviewed 
using the criteria of the Journal of Structural Biology 
(see http://www.academicpress.com/jsb). Submissions should 
be made on-line via the normal JSB submission process. In 
the cover letter please state that you wish the article to 
be considered for the Special Issue on ‘Advances in 
Electron Crystallography’ and mark for the attention of 
Ben Hankamer, Henning Stahlberg or Bob Glaeser.
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