[3DEM] Advances in Electron Crystallography of Membrane Proteins: Call for papers

[Ben Hankamer]

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Advances in Electron Crystallography of Membrane Proteins: Call for papers
for a special issue of JSB 
Ben Hankamer, Henning Stahlberg and Bob Glaeser, Guest Editors
 
The Journal of Structural Biology invites submissions for a special issue
focusing on recent ‘Advances in Electron Crystallography of Membrane
Proteins’. Electron-crystallography offers many advantages for the
determination of membrane proteins structures, which is one of the great
challenges of structural and cell biology.

In recent years electron-crystallography of membrane proteins has undergone
major developments, which enhance its natural advantages. These advantages
include the fact that membrane proteins can be crystallized within a
near-native lipid bilayer environment, that 2-D crystals may sometimes be
obtained even though 3-D crystals have not been, and that the technique is
well suited for the crystallization of small and hydrophobic integral
membrane proteins as well as membrane associated proteins.  Functionalized
monolayer technology is also opening up the possibility of streamlining
crystal production and of coupling this process to improved protein
expression techniques. As a resolution of better than 2Å has now been
reported, it is proven that data can be collected to determine not only
protein structure but its detailed interplay with the components of the
lipid bilayer.

This special edition aims to capture the key developments that will help to
take the electron crystallography field to the next phase, from streamlined
crystal production and structure determination to new levels of resolution.
Manuscripts in the following areas are specifically (but not exclusively)
invited: 

1.	Membrane protein expression
2.	Membrane protein purification
3.	2D crystallization
4.	Sample preparation for electron microscopy
5.	Automated screening of crystallization trials
6.	Computer image processing and software developments
7.	Recent applications and new structures

Papers can be in the form of research articles or mini-reviews that
summarize key areas of importance. Prior to submission of a minireview, or
if you require any further information on the suitability of your manuscript
for inclusion in this special issue, please contact Ben Hankamer
(b.hankamer at imb.uq.edu.au), Henning Stahlberg (HStahlberg at ucdavis.edu), or
Bob Glaeser (RMGlaeser at lbl.gov) .

A brief e-mail by 22 Dec 2006, stating your intent to submit a contribution
would be greatly appreciated as it would help us to plan the format of the
special issue. The deadline for receipt of manuscripts for the Special Issue
is 1 May 2006.  Manuscripts will be peer-reviewed using the criteria of the
Journal of Structural Biology (see http://www.academicpress.com/jsb).
Submissions should be made on-line via the normal JSB submission process. In
the cover letter please state that you wish the article to be considered for
the Special Issue on ‘Advances in Electron Crystallography’ and mark for the
attention of Ben Hankamer, Henning Stahlberg or Bob Glaeser.


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