[3DEM] Post-doctoral position in Leeds, UK

[John Trinick]

Astbury Centre for Structural Molecular Biology, Leeds University, UK

A post-doctoral position is available in the 
Astbury Centre at Leeds University, UK to study a 
large protein-DNA complex by electron microscopy. 
The project will mainly use cryo-electron 
microscopy and single particle analysis. It is 
planned that much of the cryo-EM data will be 
acquired using Leginon automation software, which 
is implemented on a Tecnai F20 microscope with 4k 
CCD camera. Initial screening of a variety of 
experimental conditions will use negative 
staining and preliminary reconstructions of the 
complex have already been obtained from stain 
data. In addition to the F20 microscope, 4 other 
TEMs are available, 2 equipped for frozen 
specimens. Data is analysed on a 150 processor 
linux cluster. 

The post is funded for 5 years at a starting 
salary of £26470 (~$US46k). Experience with 
cryo-EM and single particle image processing is 
desirable, but applications from other relevant 
disciplines, such as materials science and 
physics, are also encouraged.

Leeds University  has one of the largest and most 
vigorous structural biology groups in Britain 
(see www.astbury.leeds.ac.uk). The University has 
25000 undergraduates and 5000 postgraduates. 
Leeds is a thriving city and surrounding 
countryside is outstandingly beautiful.

This post will be advertised in Nature shortly. 
Informal enquiries to John Trinick



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____________________________________________________________________________
Prof. John Trinick
Astbury Centre for Structural Molecular Biology
Research Institute of Molecular and Cellular Biology
Leeds University

Office Room 6.02 Miall Building 

Postal Address
Worsley Building (Level 9)
Clarendon Way
Leeds University
Leeds LS2 9NQ, UK.

Phone/fax  44 (0)113 343 4350 (direct)

j.trinick at leeds.ac.uk

www.contractility.org



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