Tyson 1.0

[Jasper Plaisier]

Dear colleagues,

Tyson version 1.0, a tool for the 3D reconstruction of biological
macromolecules and complexes, is now available for download from:
http://www.bfsc.leidenuniv.nl/software/tyson

This is the first public release. The program has been tested 
on PC's running Mandrake Linux.
If you're interested please have a look at the website. If you
download Tyson and encounter any problems, please don't hesitate 
to contact me at plaisier at chem.leidenuniv.nl .

More details about Tyson are given below.

Kind regards,
Jasper Plaisier


Tyson was described in :
TYSON: Robust searching, sorting, and selecting of single particles in
electron micrographs, Journal of Structural Biology, in press 
(corrected proof available online)

About Tyson
===========
Tyson is a tool for the 3D reconstruction of biological macromolecules
and complexes. It was originally designed as a particle picking picking
program, and at this moment this functionality is still the main feature
of the program. Recently, however, Tyson has been completely rewritten
in a modular fashion. This modular setup allows us to incorporate
various algorithms for different steps of the reconstruction process.
The goal is to make Tyson a versatile tool for cryo-electron
microscopists by incorporating new and exciting methods.

In order to provide maximum compatibility with other existing programs,
various file-formats are supported by Tyson. Furthermore, all
information gathered in a Tyson project is stored in easily readable
XML-files. For more information on the setup of Tyson-projects and the
file-formats, check the manual or follow the tutorial on the home page.

Tyson is developed in C++ on a Mandrake Linux system. It uses Qt as a
graphical library and FFTW for calculating Fourier transforms. Tyson is
released under the GNU Public License (GPL).


Features
Below is a list of the most important features incorporated in Tyson. Be
sure, to check the list regularly, since it will be expanding rapidly.

* Micrograph view function 
* Micrograph zoom window 
* Distance measurements in micrographs 
* Particle search using local average method 
* Particle search using template method 
* Particle search using local variance method 
* Particle search in a collection of micrographs 
* Particle gallery 
* Sorting of particles for easy false positive removal 
* Quick and easy editing of particle sets 
* Merging of particle sets 
* Image export and print capabilities